Could a natural extract boost fertility treatment in PCOS?

NCT ID NCT07403201

Recruiting now Disease control Sponsor: Inlacinpenelitian Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing whether adding a natural extract called DLBS3233 to the standard fertility drug clomiphene citrate works better than clomiphene alone for women with PCOS. Researchers will measure changes in insulin resistance, ovarian function, and menstrual cycles over three months. The study involves 90 married women and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: DLBS3233 (a natural extract) combined with clomiphene citrate (a fertility drug)
What this could lead to: If it works, this combination could improve insulin resistance and ovulation in women with PCOS, offering a better treatment option than clomiphene alone.
What could go wrong: This is a very early (Phase 1) and small trial (90 people). Results may not apply to all PCOS patients, and the combination may not prove more effective or could cause side effects.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYCYSTIC OVARY SYNDROME

Contacts and locations

Locations

RS AMC Yogyakarta
RECRUITING

Yogyakarta, DIY, 55253, Indonesia

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