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127005 trials found · Page 5299 of 6351
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Simple sugar may shield catheter users from painful infections
Prevention CompletedPurpose of study To find out whether D-mannose use can prevent urinary tract infection in patients need long-term catheterization.
Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation • Aim: Prevention
Last updated Jun 27, 2026 13:07 UTC
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New nail designs tracked in leg fracture patients
Disease control CompletedThe purpose of this post-market registry is to monitor the clinical safety and performance (union rates and time to union) of two DePuy Synthes lower extremity shaft nails: RFN-Advanced Retrograde Femoral Nailing System (RFNA) and TN-Advanced Tibial Nailing System (TNA) in partic…
Sponsor: DePuy Synthes Products, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Braces breakthrough? study tests faster curing method for stronger bond
Disease control CompletedEffectiveness of One-Step Versus Two-Step Light Curing of Bonding Agent and Composite in Orthodontic Bracket Bonding: Study Design: A Randomized Controlled Trial (RCT) Study Type: Interventional Allocation: Randomized Intervention Model: Parallel Assignment Intervention Model De…
Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Liver health may change how lung cancer drug works
Knowledge-focused CompletedThe purpose of this study is to evaluate the effect of hepatic impairment on the systemic pharmacokinetics (PK), safety, and tolerability of JDQ443 in participants with varying degrees of hepatic impairment.
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Can a herbal tea tame fatty liver? new study explores
Disease control CompletedThe aim of this study is to explore the effectiveness of Jing-Si Herbal Tea on improving the Non-alcoholic fatty liver disease patients
Sponsor: Taichung Tzu Chi Hospital • Aim: Disease control
Last updated Jun 26, 2026 14:49 UTC
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Scientists peer inside lungs to unlock TB immune secrets
Knowledge-focused CompletedBackground: Tuberculosis (TB) is a lung disease. It is caused by inhaling a type of airborne bacterium. Tuberculin Purified Protein Derivative (PPD) is used to test for TB exposure. It is usually injected under a person s skin. In this study, it will be applied in the lung. Obj…
Early phase 1 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New study tests if educational videos boost cancer care for Spanish-Speaking patients
Knowledge-focused Recruiting nowThe study aims to develop educational media interventions to prepare Latinx Spanish-speaking radiation oncology patients for a course of breast or prostate cancer radiation therapy and to foster receptivity and informed decision-making around cancer clinical trial participation.
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Tiny artificial bronchus implant aims to help emphysema patients breathe
Disease control OngoingThe Pulmair Implantable Artificial Bronchus (IAB) is a device intended for implantation into the diseased bronchi of emphysema patients. The IAB is indicated for bronchoscopic treatment of adults with Chronic Obstructive Pulmonary Disease (COPD)/emphysema to relieve hyperinflatio…
Sponsor: Pulmair Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Gum surgery breakthrough? new technique saves healing tissue
Disease control Recruiting nowThe objective of this study will be to evaluate a new protocol for the surgical treatment of periodontal disease with two novelties: to make a single incision in the midline of the interproximal area to respect the vascular supply and preserve the granulation tissue with regenera…
Sponsor: Universidad de Murcia • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Probiotics for teen stress: a Gut-Brain boost?
Knowledge-focused CompletedStress is a normal human reaction to changes surrounding our reality, resulting in physical, emotional, and intellectual responses. Children and adolescents often experience high levels of stress. Age and gender may affect a child's ability to manage stress. Children and adolesce…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Mind over knee: mental coaching may boost ACL recovery confidence
Symptom relief OngoingThis study aims to determine the feasibility of implementing a mental skills training intervention for adolescent athletes who tear their ACL and undergo ACL reconstruction surgery alongside receiving standard-of-care clinical treatment. The study will also determine if the menta…
Sponsor: Boston Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Scientists peek inside Brain's fuel gauge in rare sugar disorder
Knowledge-focused Recruiting nowThe goal is to develop methodology to monitor flux in the citric acid cycle in brain via 13C nuclear magnetic resonance (NMR) spectroscopy at 7 Tesla or 3 Tesla.
Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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New study reveals breathing risks after tonsil surgery in kids with sleep apnea
Knowledge-focused Recruiting nowThis retrospective observational study aims to evaluate postoperative respiratory complications (PORC) after (adeno)tonsillectomy in children with OSA. In order to increase the number of patients available for analysis, we will merge data collected at UZA with data collected at …
Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New MRI technique could sharpen brain imaging in kids with clogged arteries
Diagnosis Recruiting nowThe MR sequence called MR-ASL is used to measure cerebral perfusion in children. This ASL sequence is used with a unique post-labeling delay (PLD) due to the technical impossibility of setting different post-labeling delays. The use of a single post-labeling, chosen by the pediat…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 26, 2026 17:26 UTC
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New study aims to prevent breathing complications after kids' sleep apnea surgery
Knowledge-focused CompletedAdenotonsillectomy is the first line surgical treatment for children with Obstructive Sleep apnea Syndrome (OSAS). Postoperative respiratory complications (PORC) may occur and are often related to co-morbidities. Despite guidelines from different scientific groups, there is no co…
Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Sitting all day? short walks may help your blood sugar
Knowledge-focused CompletedThe knowledge gap on sedentary behavior and sedentary breaks includes whether detrimental effects of sedentary behavior can be fully attenuated by 1.) sedentary breaks 2.) physical activity or 3.) both combined. Specifically, when breaking sedentary time which physical activity p…
Sponsor: Norwegian School of Sport Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New app aims to boost black Women's role in breast cancer research
Knowledge-focused CompletedThis study explores the overall feasibility, impact, and satisfaction of using the "mHealth app" on clinic workflow for Black or African American women diagnosed with breast cancer. The "mHealth app" which can be used as a platform to share clinical trial education and communica…
Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Exercise may unlock better stamina for heart failure patients
Knowledge-focused OngoingThis research in Veterans with heart failure with preserved ejection fraction (HFpEF) will provide new information on the mechanisms determining the patients' exercise intolerance and the efficacy of regular physical activity to improve this shortcoming by alleviating the patient…
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Healthy Kids' eye data may help spot diabetes damage early
Knowledge-focused OngoingThe primary goal of the project is to create a normative database from data collected from a healthy pediatric population. A secondary aim is to compare normative data with data from pediatric patients with pre-existing type 1 diabetes mellitus.
Sponsor: University Hospital Ostrava • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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New study tracks blood sugar swings across periods in type 1 diabetes
Knowledge-focused Recruiting nowIn clinical practice, women living with type 1 diabetes frequently report that insulin requirements change across the menstrual cycle. Consequently, glycemic fluctuations are observed. This phenomenon could be explained by a decrease in insulin sensitivity during the second half …
Sponsor: Institut de Recherches Cliniques de Montreal • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC