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116076 trials found · Page 5254 of 5804
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Waiting 30 seconds to clamp the cord could help tiniest babies
Disease control CompletedThis study tested the feasibility of conducting a randomized controlled trial to vary the timing that doctors clamp the umbilical cord after birth in extremely low birthweight infants. The study also tested whether delaying cord clamping by 30-35 seconds and holding the newborn a…
Phase: PHASE1, PHASE2 • Sponsor: NICHD Neonatal Research Network • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Small study aims to unlock secrets of rare lung disease
Knowledge-focused CompletedThis study will examine and test healthy volunteers and patients with pulmonary hypertension to try to learn more about the disease and find better ways to detect, treat, and, if possible, slow progression. Pulmonary hypertension is a rare blood vessel disorder of the lung in whi…
Phase: PHASE1 • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Can your genes predict prostate cancer spread?
Knowledge-focused OngoingThe overall purpose of this research is to determine if certain genes increase the chance of developing prostate cancer and once diagnosed increase the chance of the prostate cancer spreading to other parts of the body.
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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10-Year look at implant infection surgery: which method holds up?
Knowledge-focused CompletedThe purpose of this 10 year observational follow-up study was to evaluate the long-term outcomes of reconstructive surgical treatment of peri-implantitis. Two treatment approaches have been compared using a bone substitute with or without a resorbable membrane.The objective was t…
Sponsor: Kristianstad University • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Cancer gene hunt: 21,000 Patients' DNA scoured for clues
Knowledge-focused OngoingThe basic premise of this research proposal is to determine whether there is any significant association between germline polymorphisms and cancers of colon, bladder, breast, testicular, prostate, ovaries, kidney, lung, lymphoid organs, and head and neck. This is an exploratory s…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Massive study seeks answers for rare inherited nerve diseases
Knowledge-focused Recruiting nowThis study is designed to learn more about the natural history of inherited neurological disorders and the role of heredity in their development. It will examine the genetics, symptoms, disease progression, treatment, and psychological and behavioral impact of diseases in the fol…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Radiation aftermath: 700 cancer patients tracked for decades
Knowledge-focused Recruiting nowBACKGROUND * This protocol acknowledges that it is in the interest of the NIH and ROB, as well as our participants, to continue to follow those who have been treated with radiotherapy at ROB and are not otherwise eligible for current active research protocols. * It also provides…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Scientists dig into why skin tumors grow in rare disease
Knowledge-focused Recruiting nowTuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors can affect various organs, including the heart, lungs, kidneys, skin, and central nervous system, with serious medical consequences. The severity of dise…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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110 births studied: what raises the risk of uterine rupture?
Knowledge-focused CompletedThis study has for objective to collect medical data from patients with uterine rupture at the childbirth.
Sponsor: Hôpital NOVO • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Rare botulism cases reviewed to improve ICU care
Knowledge-focused CompletedBotulism poisoning is a rare but serious illness. Because of it's low incidence, it is not well known by physicians. Most studies describing botulism date back to the last century and do not take into account recent advances in intensive care. The objective of this study is to d…
Sponsor: Centre Hospitalier le Mans • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Thousands of boys studied to see if circumcision painkiller causes rare side effect
Knowledge-focused CompletedDorsal penile nerve block (DPNB) according to Dalens' technique by using local anesthetics (LAs) is a fundamental part of a multimodal analgesic approach following circumcision. Ropivacaine has a favorable cardiovascular and neurological toxicity profile. However, its application…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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1,400 kids studied to find best heart rhythm treatment
Knowledge-focused CompletedBackground Supraventricular tachycardias (SVTs) are the most common arrhythmic events in children, with an estimated incidence of 13 per 100,000 per year before the age of 18. Few large patient cohorts have been reported, as most published studies are single-center. Large-scale …
Sponsor: Paris Cardiovascular Research Center (Inserm U970) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Can doctor feedback and a diabetes nurse improve care? trial tests new strategy
Knowledge-focused CompletedThe purpose of this study is to test the effectiveness of physician profiling and care coordination by a diabetes resource nurse in improving the quality of diabetes care.
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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25-Year back surgery study: when is less really more?
Knowledge-focused CompletedThis retrospective observational study examines clinical outcomes in patients with lumbar spinal stenosis who underwent minimally invasive tubular decompression, with or without subsequent multisegmental percutaneous rhizotomy, at the General University Hospital of Valencia over …
Sponsor: University of Valencia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Pituitary patients followed for years to uncover key outcomes
Knowledge-focused OngoingTo determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Massive chinese study aims to unlock Dementia's secrets
Knowledge-focused Recruiting nowThe aim of this study is to establish and perfect the China Cognition and Aging Study (China COAST) cohort, to clarify the epidemiology, influencing factors, genetic characteristics, pathogenesis, disease characteristics and diagnosis and treatment status of dementia and its subt…
Sponsor: Capital Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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AI assistant could speed up emergency room diagnoses
Knowledge-focused OngoingThis study will evaluate the performance of a large language model (LLM)-based clinical decision support system in the emergency department at Rambam Health Care Campus. The system analyzes structured patient data from the electronic health record and generates diagnostic and tre…
Sponsor: Rambam Health Care Campus • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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8,500+ stomach cancer cases analyzed: sex differences revealed
Knowledge-focused CompletedAccording to recent statistics, the incidence and mortality from gastric cancer are both worldwide in fifth place in terms of ranking. Gastric cancer is more common in males than in females. This difference in the incidence between males and females is likely due to the differenc…
Sponsor: Medizinische Hochschule Brandenburg Theodor Fontane • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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What makes us overeat? new study probes Obesity's hidden triggers
Knowledge-focused CompletedThe prevalence of obesity in the United States has reached alarming proportions with 33% of adults over the age of 20 being overweight. Obesity is more than twice as prevalent, however, in the Pima Indians of Arizona. Although there have been a number of advances in our understan…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Scientists dig into genes to unravel IBD mysteries
Knowledge-focused ENROLLING_BY_INVITATIONInflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a idiopathic, chronic and frequently disabling inflammatory disorder of the intestines characterized by a dysregulated mucosal immune response that affect more than a million American…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC