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127005 trials found · Page 5079 of 6351
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Thousands of kids studied to uncover hidden Post-Surgery pain
Knowledge-focused CompletedFor children, adequate perioperative pain management is a right according to the UN convention on the rights of the child, a law in Sweden since 2020. Despite this, children are still under-treated in many cases. In addition to great suffering, this can lead to missing school and…
Sponsor: Region Halland • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Blindness linked to more shoulder troubles in seniors
Knowledge-focused CompletedThis case-control study aims to investigate the prevalence and determinants of shoulder girdle musculoskeletal complaints (pain, spasm, stiffness, range of motion impairments) in geriatric patients (aged 60+) with diminished vision (visual acuity \<6/60) due to Age-related Macula…
Sponsor: Beni-Suef University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New hip fracture pain block may keep leg muscles stronger
Symptom relief CompletedThe aim of this work is to compare between the use of PENG block and femoral nerve block for perioperative pain management in patients with hip fracture.
Sponsor: Beni-Suef University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New nerve block could help hip surgery patients get back on their feet faster
Symptom relief Recruiting nowThe hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier mobilisation.
Sponsor: Umraniye Education and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New DNA test could speed up diagnosis of three major parasitic infections
Diagnosis Recruiting nowThe goal is to develop molecular systems to support or replace in microscopic characterization and in vitro tests with molecular biology systems capable of improving performance in parasitology tests. In particular, we will analyze the main pathogens: several Leishmania species (…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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New Hand-Held imager aims to prevent accidental parathyroid damage in thyroid surgery
Diagnosis Stopped earlyIt is often challenging to tell apart the parathyroid glands from the surrounding area such as lymph nodes, fat and thyroid tissue. If the surgeons are not able to tell where the parathyroid glands are, they might accidentally be removed or damaged. This can lead to complications…
Phase 1 • Sponsor: OPTOSURGICAL, LLC • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Brain games for psychosis prevention: a new hope?
Symptom relief Recruiting nowStudy participants will take part in one of the two types of treatments aimed at improving daily functioning as follows: either a Cognitive Training (CT) Program or an Enhanced - Treatment as Usual (E-TAU) Group. All group treatments will be provided at Razi Hospital and one of t…
Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Teeing up for better health: golf program aims to ease prostate cancer treatment side effects
Symptom relief Recruiting nowThis clinical trial evaluates a golf recreational exercise program for enhancing survivorship in underrepresented prostate cancer survivors. Golf is a multimodal recreational activity that requires participants to utilize all muscle groups to perform the golf swing, walk over hil…
Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can a home exercise program keep seniors on their feet?
Prevention OngoingStudy Description: The investigators propose to extend earlier research conducted during a feasibility study (Strong Foundations 1.0) by enrolling participants who have a greater risk for falling (x4 cohorts of up to 15 individuals) and from a lower socio-economic status (x4 coho…
Sponsor: University of California, San Diego • Aim: Prevention
Last updated Jun 27, 2026 08:06 UTC
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Can a simple questionnaire prevent ACL injuries in youth sports?
Knowledge-focused By invitation onlyThis study aims to investigate if a detailed and comprehensive survey can identify, explain and prevent the risk factors for ACL injury. A a new questionnaire has been developed with questions to young athletes who have suffered an anterior cruciate ligament injury. The question…
Sponsor: Linnaeus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Sound waves could spot early signs of rare muscle disease
Knowledge-focused CompletedFacioscapulohumeral muscular dystrophy (FSHD) is characterized by early and significant involvement of facial muscles; however, objective imaging data focusing on facial muscles are limited. Facial ultrasound can serve as a sensitive imaging biomarker and outcome measure by captu…
Sponsor: Koç University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Shake or run? study tests best exercise after kidney transplant
Disease control CompletedThis study aimed to compare the effect of whole body vibration versus aerobic training on interleukin 6 and endurance after renal transplantation in patients after renal transplantation.
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Hidden muscle loss common in GI cancer patients, study finds
Knowledge-focused CompletedSarcopenia is a syndrome characterized by progressive loss of skeletal muscle mass and strength and is associated with worse outcomes in cancer patients. It can negatively affect prognosis, increase postoperative complications, reduce tolerance to systemic therapy, and impair qua…
Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New tool helps COPD patients make tough end-of-life decisions
Knowledge-focused CompletedThis study aims to support EOL decision-making in patients with advanced COPD and their family members. A parallel two-arm single-blinded randomised controlled trial will be conducted to evaluate the effects of a specific decision support intervention. A total of 226 patients wit…
Sponsor: Food and Health Bureau, Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Eye gel may replace painful needle in pterygium surgery
Symptom relief CompletedIn pterygium excision procedures, the subconjunctival injection of xylocain is regarded as an uncomfortable and painful step in the procedure. While already being studied in other ophthalmic procedures such as glaucoma surgery (7), application of topical lidocaine gel is likely t…
Phase 4 • Sponsor: Vrije Universiteit Brussel • Aim: Symptom relief
Last updated Aug 27, 2026 00:00 UTC
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French study tracks unusual rise in child mycoplasma infections
Knowledge-focused CompletedThis study was set up because of an unusual increase in the number of cases of mycoplasma infections in France between June and November 2023. Clinical data from children with mycoplasma infections will be collected to characterise this infection and facilitate hospital manageme…
Sponsor: Association Clinique Thérapeutique Infantile du val de Marne • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Which IV fluid spares kidneys best during back surgery in seniors?
Knowledge-focused CompletedThis study aims to compare the effects of sodium acetate Ringer's solution versus sodium lactate Ringer's solution on early postoperative renal function indicators, renal injury biomarkers, and acute kidney injury (AKI) in elderly patients undergoing lumbar fusion surgery.
Sponsor: Xianping Wu • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Bubbly water may keep you from fainting
Symptom relief Recruiting nowThe primary purpose of this investigation is to determine whether water carbonation can improve orthostatic tolerance in healthy control volunteers. Orthostatic tolerance refers to the ability to maintain an adequate blood pressure when standing. In some individuals blood pressur…
Sponsor: Simon Fraser University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Zapping the brain to boost therapy: small study tests new approach
Knowledge-focused CompletedThe purpose of the proposed study is to examine if a repeated treatment of High Definition Transcranial Direct Current Stimulation (HD-tDCS) can increase the functional connectivity between the left ventrolateral prefrontal cortex and posterior cingulate, which may further enhanc…
Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New brief therapy aims to help veterans in opioid recovery find purpose
Symptom relief Recruiting nowThe US Veteran community continues to feel the impact of the overdose crisis, and opioid use disorder (OUD) diagnoses among Veterans continue to rise. Medication treatment (e.g., buprenorphine, methadone, naltrexone) helps prevent relapse and reduce overdose risk, but does not he…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC