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116076 trials found · Page 5049 of 5804
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New study tracks hidden struggles of rare head and neck cancer survivors
Knowledge-focused Recruiting nowTo learn about the symptoms and changes our patients experience while receiving treatment for sinonasal or nasopharyngeal cancer
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New program helps cancer patients and caregivers talk through tough emotions
Symptom relief OngoingThis study will test an intervention to improve patients' and their caregivers' ability to manage difficult emotions and communicate about the patient's illness. There will be two versions of the intervention used for this study: a culturally tailored version for Latinx participa…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New antibody drug shows promise in early arthritis trial
Disease control CompletedThis study will assess the safety and pharmacokinetic comparability of two VAY736 drug products in patients with rheumatoid arthritis.
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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One-Dose steroid may cut Kids' pain after tonsil removal
Symptom relief CompletedThis research study aims to find out if a single oral dose of steroid after tonsillectomy will reduce pain and decrease the need for narcotic medications.
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Scientists launch global effort to unlock mysteries of rare blood disorder
Knowledge-focused Recruiting nowThis is an Investigator initiated retrospective and prospective single cohort study. The study will utilize an international registry and develop a specimen biobank to provide an improved understanding of the natural history of hyposplasminogenemia, to elucidate the heterogeneity…
Sponsor: Indiana Hemophilia &Thrombosis Center, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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New diagnostic strategy aims to end diagnostic odyssey for rare diseases
Diagnosis CompletedThe principal aim of the study is to avoid the diagnostic wanderings of patients suffering from a peroxisomal disorder. For this purpose, a new diagnostic strategy is proposed. It rests on functional metabolic explorations and gene studies directly connected to a first-line enlar…
Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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New registry monitors VBX stent graft in Real-World use
Knowledge-focused OngoingThe primary objective of the VBX 17-04 registry is to collect post-market safety and performance data of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis (VBX Stent Graft) in peripheral vessels in patients who require interventional treatment
Sponsor: W.L.Gore & Associates • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Hands-On therapy may soothe alcohol withdrawal
Symptom relief CompletedThe alcohol withdrawal syndrome has a hierarchical symptomatology depending on the severity (minor, moderate or severe). These signs express a state of psychic, behavioral and physical deprivation. The management of withdrawal syndrome involves the establishment of pharmacologic…
Phase: NA • Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Smart oxygen machine aims to get COPD patients out of hospital faster
Disease control TerminatedThe aim of this study is to evaluate if automated adjustment of oxygen (with FreeO2 device) can reduce the hospital length of stay for acute exacerbation of COPD with comparison of manual oxygen titration.
Phase: NA • Sponsor: Laval University • Aim: Disease control
Last updated Jun 26, 2026 14:17 UTC
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Warm eyelid treatment shows promise for dry eye sufferers
Symptom relief CompletedThe objective of the study is to evaluate the long-term clinical utility, safety, and effectiveness of re-treatment with the TearCare™ System in adult patients with dry eye syndrome who had previously been treated with the TearCare System.
Phase: NA • Sponsor: Sight Sciences, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Knee surgery debate: to keep or remove the fat pad?
Knowledge-focused CompletedThis study aims to compare the postoperative clinical outcomes of Infrapatellar Fat Pad (IPFP) preservation versus resection after total knee arthroplasty (TKA) in patients with knee osteoarthritis. Participants will be identified as normal IPFP or abnormal IPFP based on MRI find…
Phase: NA • Sponsor: Zhujiang Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Study reveals work struggles for thoracic outlet syndrome patients
Knowledge-focused CompletedThoracic outlet syndrome may associate neurologic, arterial and venous symptoms. The responsibility of repetitive movements and postural factors has been mentioned for long. Some tasks are hard to perform, and it seemed interesting to assess the consequences of this syndrome on t…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Funnel chest surgery: does it really improve breathing and heart health?
Knowledge-focused CompletedThe main objective of this study is to characterize the cardiorespiratory functional gain in patients with pectus excavatum following corrective surgery.
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New computer tool aims to help lupus patients choose treatments
Knowledge-focused CompletedThe study will attempt to put into practice a shared decision making (SDM) strategy, using an individualized, computerized decision- aid (DA) for Systemic lupus erythematosus (SLE).
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Could inflammation after newborn seizures predict epilepsy?
Knowledge-focused CompletedThe purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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ALS drug trial halted early: what happened?
Disease control TerminatedThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple oral doses of DNL747 in subjects with Amyotrophic Lateral Sclerosis in a cross-over design
Phase: PHASE1 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Therapy gets digital: study tests if reading your texts boosts mental health
Knowledge-focused CompletedThis randomized control trial aims to establish whether viewing and discussing patients' electronic communication (texts, emails, Facebook direct messaging, etc) impacts clinical care and decision making across the lifespan.
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Brain injury study tracks memory Self-Awareness during recovery
Knowledge-focused OngoingThe purpose of this study is to investigate the trajectory of metacognitive functioning throughout phases of recovery from neurological insult, and to determine its relationship to rehabilitation compliance and functional outcome. It is hypothesized that metacognitive accuracy im…
Sponsor: University of Nebraska Lincoln • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Kids' drug dosing mystery: new study aims to crack the code
Knowledge-focused Recruiting nowThe purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Sponsor: Chi Dang Hornik • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Capsule camera data could sharpen disease detection
Knowledge-focused CompletedObservational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports
Sponsor: Medtronic - MITG • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC