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116076 trials found · Page 5028 of 5804
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Brain scans reveal how aging changes emotional reactions
Knowledge-focused CompletedIt is accepted that emotional events engage more attention and are detected and identified faster than neutral events. The same is true of negative events with regard to positive events. At the cerebral level, this facilitation results in greater activation of brain regions invol…
Phase: NA • Sponsor: University Hospital, Grenoble • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Open-Source hearing aid could make better hearing more accessible
Knowledge-focused CompletedDetermining acceptability and usability of a wearable open-source speech processing platform (Master Hearing Aid) developed for hearing-aid research
Sponsor: San Diego State University • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Lateral kangaroo care may be as safe as prone for tiny preemies
Knowledge-focused CompletedThe objetive of the study is to evaluate the non-inferiority or the equivalence of the kangaroo care position, in lateral versus traditional one in prone measuring the stability of several parameters in premature infants less than 28 weeks of gestational age during the first 5 da…
Phase: NA • Sponsor: Laura Collados Gomez • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Braces pain showdown: researchers test which wire is gentlest
Symptom relief Recruiting nowThree different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective. It is possible that one type of wire engenders more patient disc…
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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ER sedation gets a tech upgrade: Computer-Controlled propofol tested
Symptom relief CompletedProcedural sedation is an emergency medicine technique that provides a brief, deep sedation in order to perform very painful emergency emergent procedures such as displaced fracture or dislocated joints reduction. Propofol is recommended for this purpose, injected administered in…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Blood tests could reveal who reacts differently to radiation
Knowledge-focused OngoingPeripheral blood samples will be taken with informed consent from radiotherapy patients before and during treatment fractions for sarcoma, breast, lung, gut, genitourinary and head \& neck tumours at The Royal Marsden. Candidate genes identified by PHE, Columbia and/or in the lit…
Sponsor: Institute of Cancer Research, United Kingdom • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Fingerprick test for blood thinners put to the test
Diagnosis CompletedThis study is to evaluate the INR levels in patients taking phenprocoumon using the LumiraDx Point of Care INR test and comparing the results to the laboratory reference method , the ACL Elite Pro. Comparison will also be made with the Roche Coaguchek point of care INR test (poin…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Tiny coil placed inside nose could help surgeons spot hidden brain tumors
Knowledge-focused Recruiting nowTumors of the pituitary gland comprise up to 20% of all brain tumors. The central location and the small size of the pituitary gland make the management of tumors particularly challenging. Transsphenoidal surgery (TSS) to resect pituitary tumors is highly successful at achieving …
Phase: NA • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Double nerve block may cut opioid use after lung surgery
Symptom relief CompletedMonocentric, randomized, controlled, single-blind study who's aim is to demonstrate the efficacy of the association of paravertebral block and serratus plane block with paravertebral block alone
Phase: PHASE4 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Scientists launch national effort to unravel mysteries of rare blood disorder
Knowledge-focused Recruiting nowUnexplained chronic hypereosinophilia (HE) and hypereosinophilic syndromes (HES) are heterogeneous regarding the organ involvements (heart, lungs, skin, .. or none), the evolutionary profiles, the response to treatments. Underlying mechanisms are largely unknown and may associat…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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New laser device could revolutionize eye disease detection
Knowledge-focused Recruiting nowThis study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other visual function tests.
Phase: NA • Sponsor: Randy Kardon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Scoliosis study aims to uncover hidden physical deficits in adults
Knowledge-focused Recruiting nowAdults with scoliosis have not been the focus of much research in physical therapy despite their prevalence being very important. Adults with idiopathic scoliosis have a reported prevalence of about 2-11%. This includes adolescents with idiopathic scoliosis who have become adults…
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Could dissociation play a role in obesity?
Knowledge-focused CompletedTHe aim of this study is to determine the frequency of dissociative tendencies in the obese population treated at the CELIOBE (Liberal Center for Obesity Support) at Hôpital Privé La Louvière among patients consulting for the first time and looking for a medical or surgical cours…
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Knee implant study seeks best surgical alignment
Knowledge-focused CompletedThe purpose of this study is to compare migration patterns between mechanical and anatomic alignment surgical techniques for the Attune S+ CR-FB knee system using model-based RSA over the first 2 post-operative years.
Phase: NA • Sponsor: Canadian Radiostereometric Analysis Network • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Study reveals artery stiffness from common cancer drug
Knowledge-focused CompletedAntiangiogenic treatments are used in many tumor locations such as metastatic colorectal cancer (mCRC) with a significant improvement in carcinological results on overall survival and / or progression-free survival. However, their use is characterized by an increase in side effec…
Phase: PHASE4 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Liver fat during pregnancy may signal future diabetes risk
Knowledge-focused OngoingThe aim of this study is to utilise ultrasound, using an established method for detecting NAFLD, to determine whether the presence of NAFLD in women with GDM, detected during routine scanning, is a marker of deterioration in glycaemic status post-partum. We propose to assess the …
Sponsor: University Hospitals of North Midlands NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Camera pill reveals gut nerve secrets in Parkinson's
Knowledge-focused ENROLLING_BY_INVITATIONThe goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Heart risk after chemo: scientists hunt for clues in your blood
Knowledge-focused Recruiting nowThis study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Could a brain hormone fix low sex hormones? small study hints at possibility
Knowledge-focused CompletedThe goal of this study is to develop novel treatments for patients with a condition called hypogonadotropic hypogonadism (HH) through the use of exogenous kisspeptin.
Phase: PHASE2 • Sponsor: Stephanie B. Seminara, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Mom's weight before pregnancy linked to Baby's growth and food preferences?
Knowledge-focused Recruiting nowThe goal of this observational study is to investigate the concentrations of leptin, insulin, liver expressed antimicrobial peptide 2 (LEAP2), and cortisol in plasma and breast milk and their relationship with eating behavior, growth, adiposity and with the levels of these hormon…
Sponsor: Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC