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116076 trials found · Page 4991 of 5804
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Back pain breakthrough: teaching brain science beats old advice
Symptom relief CompletedThe hypothesis is that pain biology education, combined with a rehabilitation program, reduces disability to 3 months, compared to conventional spinal physiology education.
Phase: NA • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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New pain drug shows promise in small tummy tuck study
Symptom relief CompletedEvaluate the Safety and Pharmacokinetic Profile of CPL-01 in patients after mini-abdominoplasty
Phase: PHASE2 • Sponsor: Cali Pharmaceuticals LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Tracking hospital staff: does more time with patients save lives?
Knowledge-focused CompletedThis study will examine the productivity of the hospital workforce utilizing a unique dataset that is stored at the Royal Wolverhampton Trust (RWT). The data is recorded by a Real Time Location System (RTLS) that tracks the second-by-second physical location of patients, staff, a…
Sponsor: The Royal Wolverhampton Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Stem cells tested for safety in advanced lung disease
Symptom relief CompletedResearchers are trying to understand the effects of mesenchymal stem cells therapy in subjects with advance chronic obstructive pulmonary disease
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Eye scans may spot early damage from sleep apnea
Knowledge-focused CompletedObstructive sleep apnea syndrome (OSA) is thought to lead to systemic vascular lesions that may be preceded by early microvascular lesions in the eyes and in particular in the retina. The improvement of ophthalmological imaging techniques by OCTangiography allows a precise non-in…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New hope against deadly molds? early trial cut short
Disease control TerminatedThis is a Phase 2, multicenter study to evaluate APX001 for the treatment of invasive fungal infections caused by Aspergillus spp. or rare molds (eg, Scedosporium spp., Fusarium spp., and Mucorales fungi).
Phase: PHASE2 • Sponsor: Basilea Pharmaceutica • Aim: Disease control
Last updated Jun 26, 2026 17:54 UTC
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New pain block aims to cut opioid use after kidney surgery
Symptom relief TerminatedNephrectomy (kidney removal) is one of the most common surgical procedures in urologic practice. Recent advances in laparoscopic (keyhole) procedures have resulted in a significant decrease in open nephrectomies. Most laparoscopic surgeries are performed through 3 to 4 small (1 t…
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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New program brings relief to older black women struggling with pain and sadness
Symptom relief CompletedAfrican American women who are 50 years of age and older with depressive symptoms, pain and difficulty with mobility will participate in the DAPPER intervention study that includes 8 nurse visits in participants' homes to help participants with participants' pain and mood.
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Micro heart lead shows promise in early test
Disease control CompletedPilot study to evaluate the performance of a lead below 2 French with specific distal shape to deliver efficient LV pacing
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Can cutting salt calm rheumatoid arthritis? new study investigates
Knowledge-focused CompletedIn this study investigators propose to address the following hypotheses: 1) Reduction in dietary sodium will decrease inflammation in patients with rheumatoid arthritis (RA). 2) Reduction in dietary sodium will decrease blood pressure in patients with RA. 3) Reduction in dietary …
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Wisdom tooth healing boosted by blood gels and laser?
Knowledge-focused CompletedSurgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing. Various regenerative techniques are used to improve healing outcomes after tooth extraction. This…
Phase: NA • Sponsor: Medical Innovation Center Wroclaw • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Mental health study aims to uncover Long-Term heart risks
Knowledge-focused TerminatedIn the current project, primary health care patients with mental illness such as anxiety, depression, fatigue or sleep disorders will be followed. The study includes both health conversations with the health curve as a systematic work with lifestyle habits, and the biochemical ri…
Phase: NA • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Which HSG method hurts less and shows more? study puts three techniques to the test
Diagnosis CompletedDifferent techniques have been developed to optimize hysterosalpingography (HSG) methodology. Our aim is to compare the advantages and disadvantages of these three different techniques in terms of both patient satisfaction and clinician's interpretation. The medical records of th…
Phase: NA • Sponsor: Medipol University • Aim: Diagnosis
Last updated Jun 27, 2026 12:33 UTC
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Walking sooner after ankle surgery: does it help?
Knowledge-focused CompletedThe overall objective of this study is to compare outcomes following early versus delayed weight bearing for adult patients operatively treated for an ankle fracture without syndesmotic fixation. Additionally, early weight bearing will be tested in patients with unicondylar plate…
Phase: NA • Sponsor: Major Extremity Trauma Research Consortium • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Blood transfusion trends in trauma: what worked and what Didn't?
Knowledge-focused CompletedThis retrospective cohort study evaluated transfusion practices and outcomes in 137 severely injured trauma patients requiring massive transfusion at a Level I trauma center (2020-2025). This study analyzed balanced transfusion ratios, whole blood (WB) use, thromboelastography (T…
Sponsor: Mariah Arif • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Heart shock test during ICD implant may leave no trace, study suggests
Knowledge-focused CompletedResearchers are trying to determine if heart injury occurs in patients with a cardiac implantable electronic device (CIED) who undergo a defibrillation threshold testing (DFT) procedure.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Can computer predict your new face after jaw surgery? study says maybe.
Knowledge-focused CompletedThis study aims to evaluate the accuracy of "Dolphin 3D" software for prediction of soft tissue changes in management of patients seeking orthognathic surgery to treat their mandibular deformities and collecting their feedback regarding aesthetic satisfaction.
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Which surgery is safer for esophageal cancer? new study compares two techniques
Knowledge-focused CompletedSurgery is still the main treatment for esophageal cancer, however, the complication and mortality rate of open esophagectomy is high. As a result, the thoracoscopic- laparoscopic minimally invasive esophagectomy (MIE) was developed. The MIE mainly comprised two surgical approach…
Phase: NA • Sponsor: The Second Hospital of Shandong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Nationwide french study aims to settle debate on best way to remove large colon polyps
Knowledge-focused Recruiting nowInitially developed in Japan for the treatment of endemic superficial gastric cancers, endoscopic submucosal dissection (ESD) allows resection of pre-neoplastic and neoplastic lesions of the digestive tract into a single fragment. It allows a perfect pathological analysis, and de…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:05 UTC
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Common nausea drug beats ketamine in stopping Post-Surgery shivers
Symptom relief CompletedThis randomized controlled trial assessed whether intravenous ondansetron is more effective than low dose ketamine in preventing shivering after spinal anesthesia in adults undergoing elective surgery. Post spinal shivering is a frequent and uncomfortable complication of spinal a…
Phase: NA • Sponsor: Mayo Hospital Lahore • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC