Thinner needle for thyroid biopsy may reduce pain without sacrificing accuracy

NCT ID NCT07683039

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study compares two needle sizes (21-gauge vs 27-gauge) used for ultrasound-guided fine needle biopsy of thyroid nodules. The goal is to see which size causes less pain and discomfort during the procedure while still collecting enough cells for diagnosis. Adults with thyroid nodules needing biopsy are randomly assigned to one needle size, and pain is measured right after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If one needle size causes less pain without affecting sample quality, it could become the preferred choice for thyroid biopsies, improving patient comfort.
What could go wrong
This is a small, single-hospital study. Results may not apply to all patients or settings, and the smaller needle might yield fewer adequate samples.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • İzmirAtatürk Training and Education Hospital

    Izmir, 35620, Turkey (Türkiye)

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