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116076 trials found · Page 4913 of 5804
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Dental implant depth showdown: 4mm vs 6mm – which saves more bone?
Knowledge-focused CompletedThe aim of a study was to analyze the effect of implant placement depth (4 mm versus 6 mm below the mid-facial gingival margin) on marginal bone loss (MBL) around implant and implant stability during immediate implant placement after tooth extraction. Clinical trial was conducted…
Phase: NA • Sponsor: Tomas Linkevicius • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New study tracks RSV ear infections in kids
Knowledge-focused Recruiting nowStrengthening outpatient low respiratory tract infection surveillance to document the burden of Respiratory Syncytial Virus (RSV)
Phase: NA • Sponsor: Association Clinique Thérapeutique Infantile du val de Marne • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Hair salons offer more than a trim: HIV prevention and birth control on offer
Prevention CompletedThe investigators propose to offer a package of evidence-based health services to women in two hair salons in the Umlazi township of Durban. Based on community feedback in previous survey and qualitative work, the package has been designed to include daily PrEP, family planning/c…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:36 UTC
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Autism blood test study aims to reduce stress
Knowledge-focused Recruiting nowThe project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test in common practice.
Phase: NA • Sponsor: Centre Hospitalier Charles Perrens, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Could thin air help failing hearts? small study cut short
Symptom relief TerminatedHeart failure impairs quality of life and exercise capacity, despite an optimal medical therapy. Alternative methods, like hypoxic conditioning coupled to exercise training, must be explored and describe
Phase: NA • Sponsor: University Hospital, Grenoble • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Premature Babies' vision tracked years after ROP treatment
Knowledge-focused OngoingPrimary objectives of the study are: * To evaluate binocular visual acuity at the end of this study in patients included from the VGFTe-ROP-1920 study, for treatment of Retinopathy of Prematurity (ROP). * To evaluate long-term safety outcomes in patients included from the VGFTe-…
Sponsor: Regeneron Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Mild COVID cases mount strong immune defense, study finds
Knowledge-focused CompletedThe purpose of this study is to describe the immunological and virological response of patients infected with CoV-2-SARS and presenting an asymptomatic or mildly symptomatic form, in particular the innate and adaptive response as well as the virological clearance kinetics. The r…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Gum graft boosts implant infection repair?
Disease control CompletedThe study will aim to compare two modalities in the reconstructive treatment of peri-implantitis defects. More specifically, the control group will be a reconstructive approach (xenograft bone graft granules and collagen membrane, BioOss and BioGide, Geistlich, Wolhusen). The tes…
Phase: NA • Sponsor: George Eastman Dental Hospital, Italy • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Thigh injection may stop blood pressure spike during surgery
Symptom relief Recruiting nowThe goal of this prospective randomized double-blind study is to determine if an ultrasound guided peri-arterial injection of local anesthetic (LA) superomedially the femoral artery via peripheral nerve catheter reverses ischemic hypertension associated with prolonged lower extre…
Phase: PHASE4 • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New powered knee shows promise for amputees with low mobility
Symptom relief CompletedThis was a prospective case series design investigation with 6 prosthesis user subjects. Subjects performed the Timed up and go (TUG) test and the two minute walk test (2MWT) along with some activities of daily living (ADL), on their prescribed knee as well as the investigational…
Sponsor: Össur Iceland ehf • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New app aims to ease stress for child care providers and parents during COVID-19
Symptom relief ENROLLING_BY_INVITATIONThe investigators aim to deliver a tele-wellness supported app to Baltimore City's Family Child Care Home (FCCH) providers who are caring for children of Essential Personnel. Once a pre-survey is conducted, login information will be assigned to 30 Family Child Care Home providers…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New dressing could heal painful HS wounds
Symptom relief CompletedThe objective of this case series is to monitor time and outcome of healing of wounds associated with HS using Endoform \[ovine forestomach\], Hydrofera Blue \[methylene blue and gentian violet\], and Hypafix tape. a combination methylene blue, gentian violet, and ovine forestoma…
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New shorter radiation regimen tested for endometrial cancer
Disease control CompletedStudying adjuvant hypofractionated whole pelvis radiation therapy in Endometrial Cancer.
Phase: NA • Sponsor: Teresa Meier • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Hidden bone loss: HIV and cancer patients under the scanner
Knowledge-focused OngoingBackground: Some people with human immunodeficiency virus (HIV) are on antiretroviral therapy (ART). Their cells have shown to age faster than expected. This puts them at higher risk for a range of age-related diseases about 10 years sooner than people who do not have HIV. Low b…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Blood samples could reveal hidden heart risks
Knowledge-focused Recruiting nowThe main goal of this project is to constitute a collection of biological samples, obtained through the clinical activity of the Centre for Screening and Prevention of Atherosclerosis at Toulouse University Hospital, managing patients in primary or secondary prevention for cardio…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Cell sheet trial for esophageal cancer patients ends early with just one volunteer
Disease control TerminatedThe purpose of this study is to evaluate the efficacy and safety of esophageal epithelial regenerative treatment by the transplantation of the product, CLS2702C, to the esophageal wound site after extensive ESD for superficial esophageal cancer in the steroid administration risk …
Phase: PHASE3 • Sponsor: CellSeed Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Sexual health in arthritis patients under the microscope
Knowledge-focused Completedtudy Description Definitions Use this module to describe the study protocol. * Required * § Required if Study Start Date is on or after January 18, 2017 \[\*\] Conditionally required Brief Summary \* Use these resources to provide understandable information about this study t…
Sponsor: Altuğ Güner • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Japanese breast cancer survival data reviewed for palbociclib combo
Knowledge-focused CompletedThis is a retrospective, multicenter, observational study in Japan. The primary objective is to evaluate overall survival (OS) in Japanese patients with HR+/HER2- advanced breast cancer who have been treated with palbociclib plus letrozole. This observational study was planned as…
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Leg lift test may predict blood pressure drops in C-Section patients
Knowledge-focused CompletedSpinal anesthesia for cesarean section is associated with a high incidence of low blood pressure. However, the pathophysiology of this arterial hypotension is not unequivocal and could involve, in addition to drug vasoplegia, a mechanical cause linked to lower caval compression o…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:40 UTC
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Discarded tumor tissue yields clues for future brain cancer therapies
Knowledge-focused CompletedThis study examines tumor tissues and blood samples to aid in the development of therapies for brain cancer and other solid tumors. Studying samples of blood and tissue from patients with glioblastoma or other solid tumor in the laboratory may help doctors understand brain tumors…
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC