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116076 trials found · Page 4681 of 5804
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Hidden patterns: how three chronic diseases often travel together
Knowledge-focused CompletedImproved medical care has led to an increase in both the age and clinical complexity of patients admitted to Internal Medicine wards, characterized by multiple chronic diseases. Multimorbidity is a common issue in the elderly, significantly associated with higher mortality, funct…
Sponsor: Fadoi Foundation, Italy • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Smartphone app may predict recovery in older surgery patients
Knowledge-focused Recruiting nowThis is a prospective observational study looking at gait-cadence in older adults who are scheduled to have major abdominal surgery at the University of Chicago. The objective of the study is to evaluate whether gait-cadence, as measured from a patient's mobile device at-home, ca…
Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can a box of exercise gear boost Seniors' health? hong kong study says yes
Knowledge-focused CompletedThe goal of this clinical trial is provide a scientific evaluation on the impact of the Jockey Club Get Fitness Campaign to improve the physical capacity and health condition of the community-dwelling older adults after the COVID-19 pandemic. Participants will take part in any of…
Phase: NA • Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Which nerve block is best for hip replacement pain?
Symptom relief CompletedThe hip joint is the largest and one of the most stable joints in the human body. It bears the majority of the body's weight during both dynamic and static activities, making it highly susceptible to degenerative diseases, particularly in the elderly population. In advanced cases…
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Chilean pain study reveals hidden toll on mental health
Knowledge-focused CompletedThe present study seeks to follow up the cohort of adults representative of Chile's urban population whose levels of chronic pain were evaluated in March 2023 (baseline) as part of the Mental Health Thermometer (MHT) study. The study consists of a 12 month follow-up telephone int…
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Robotic surgery may speed recovery for polycystic kidney patients
Knowledge-focused OngoingThe goal of this observational prospective cohort study is to evaluate the feasibility, safety, and postoperative outcomes of robotic-assisted unilateral native nephrectomy using the Medtronic Hugo™ RAS system compared with the open surgical approach in patients with autosomal do…
Sponsor: University of Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New imaging tools aim to take the guesswork out of muscle pain diagnosis
Diagnosis CompletedMyofascial pain syndrome (MPS) is highly prevalent in the community. It is primarily diagnosed using patient self reports and physical examination, which lack reliability, sensitivity and specificity and does not provide insights into the abnormal biological and physiological pro…
Sponsor: George Mason University • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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Simple blood test may spot newborns at risk for lung trouble
Diagnosis CompletedThis trial is intended to assess the serum levels of interleukin-6 as a predictive factor for the occurrence of meconium aspiration syndrome in infants born with MSAF.
Phase: NA • Sponsor: Benha University • Aim: Diagnosis
Last updated Jun 27, 2026 09:02 UTC
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850 knee patients tracked to uncover why MPFL surgery sometimes fails
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability. The main questions it aims to answer are: * What are the risk factors for recurrent patellar instabili…
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Music eases anxiety during pregnancy checkups, study finds
Symptom relief CompletedThis study evaluated whether listening to music during routine non-stress test (NST) monitoring affects fetal parameters and maternal psychological outcomes. NST is a common prenatal assessment, and some pregnant women may experience anxiety or negative emotions during the proced…
Phase: NA • Sponsor: Biruni University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Psychiatry's hidden risks: new study probes malpractice in mental health clinics
Knowledge-focused CompletedMalpractice in psychiatry is the failure of mental health professionals to meet accepted standards of care, resulting in harm to patients. While considered less risky than other specialties, the nature of psychiatry presents unique challenges and legal risks. This descriptive an…
Sponsor: Abant Izzet Baysal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New root canal filler could improve tooth survival
Disease control OngoingThis randomized clinical study analysed the clinical use of a new bioceramic premixed CaSi-containing sealer in association with a warm carrier-based technique or a traditional epoxy resin based sealer. Methodology: Healthy patients requiring root canal treatments were enrolled.…
Phase: NA • Sponsor: University of Bologna • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Can we skip opioids in Weight-Loss surgery? new study tests safer pain control
Symptom relief Recruiting nowThe goal of this clinical trial is to compare Opioid Free and Opioid Based Anaesthesia in patients undergoing sleeve gastrectomy. The main questions it aims to answer are: * Will the total dose of intraoperative opioid be reduced? * Will there be difference in pain scores betwee…
Phase: NA • Sponsor: G.Gennimatas General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Vacuum bandage may speed healing after skin grafts
Symptom relief CompletedSplit-thickness skin grafting (STSG) is a cornerstone of reconstructive surgery, but donor sites often experience significant morbidity due to partial-thickness wounds created. Accelerating the re-epithelialization of these donor sites is crucial for minimizing complications. Neg…
Phase: NA • Sponsor: Mahmoud Abdalla Hifny Taha • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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New nursing strategy aims to cut ICU infections
Disease control CompletedThis study aims to evaluate the impact of a multidisciplinary collaborative bundle nursing intervention based on targeted surveillance on the incidence of ICU device-associated infections (DAIs). The control group received routine nursing care, while the intervention group implem…
Phase: NA • Sponsor: The First Hospital of Qinhuangdao • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Heart bypass breakthrough? new imaging may boost graft success
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about the long-term effects of Quantitative Flow Reserve (QFR) assessment in patients undergoing Coronary Artery Bypass Grafting (CABG). The main question it aims to answer is: Does preoperative QFR measurement improve graft outco…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can we cut unneeded blood tests in Kids' ICUs? new study aims to find out
Knowledge-focused OngoingThis study will compare two strategies that target distinct determinants of blood culture overuse in an exploratory, hybrid, pilot trial in 8 PICUs. It aims to determine if there is any association between specific strategies used to reduce blood culture overuse on unit-wide bloo…
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Blood infection clues: low hemoglobin and frequent sampling may raise PICC risks
Knowledge-focused CompletedThis retrospective cohort study aims to evaluate the incidence and clinical predictors of Central Line-Associated Bloodstream Infections (CLABSI) in patients receiving Peripherally Inserted Central Catheters (PICCs) via the Anesthesia Department.
Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New study aims to spot which newborns will get worse from deadly gut disease
Knowledge-focused CompletedThis is a retrospective study led by The Sixth Affiliated Hospital, Sun Yat-sen University, focusing on newborns diagnosed with necrotizing enterocolitis (NEC)-a serious gastrointestinal disease that threatens newborns' lives-between January 2023 and June 2025. Purpose of the st…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Which surgery best fights knee replacement infections? study digs into data
Knowledge-focused CompletedA single-center retrospective cohort study was conducted in the Department of Orthopedics, the First Affiliated Hospital of Fujian Medical University. This study reviewed 145 patients who underwent debridement, antibiotics, and implant retention (DAIR), 1-stage revision, 1.5-stag…
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC