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127005 trials found · Page 4612 of 6351
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New pillow eases leg vein symptoms overnight?
Symptom relief CompletedThe goal of this single-arm clinical trial is to learn whether overnight limb elevation using the UZit® device can improve symptoms and signs of chronic venous disease (CVD) in adults. The main questions it aims to answer are: Does one week of overnight UZit® use improve quality…
Sponsor: Universidade do Porto • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Heart disease and inflammation: new study seeks answers
Knowledge-focused Recruiting nowThis is a cohort study to investigate the clinical features, current treatment and clinical outcomes in patients with inflammation-associated non-rapidly-progressive coronary artery disease (INR-CAD).
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New glucose monitor put to the test for people with type 1 diabetes
Diagnosis Recruiting nowThe study is to evaluate the accuracy and safety of a novel real-time CGM system among adult patients with type 1 diabetes mellitus with respect to YSI reference venous plasma sample measurements.
Sponsor: Henan University of Science and Technology • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Herbal extract may flush out tiny kidney stone remnants
Disease control Recruiting nowThe purpose of this study is to evaluate the efficacy of a specialized formula of phytotherapeutic extracts (Neorenal Forte) aiding the complete elimination of residual fragments after fURS in adults.
Sponsor: Neopharm Bulgaria Ltd. • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Muscle loss may mess with Seniors' balance and pain
Knowledge-focused OngoingThe aim of this observational study is to reveal the effect of sarcopenia on cervical proprioception, kinesiophobia and pressure pain threshold in geriatric individuals living in a nursing home. The main questions it aims to answer are as follows: The presence of sarcopenia in g…
Sponsor: Atılım University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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CT scan helps doctors avoid nerve damage during heart procedure
Knowledge-focused CompletedThe anatomical location of the right phrenic nerve (RPN) in close proximity to the right pulmonary veins has become a critical consideration for electrophysiologists performing pulmonary vein isolation, the cornerstone treatment for atrial fibrillation. Although radiofrequency ab…
Sponsor: Centro Medico Teknon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New combo therapy shows promise for stiff knees
Symptom relief CompletedThis study aims to evaluate the effectiveness of integrating Muscle Energy Technique (MET) and Mulligan Mobilization with conventional physical therapy in the management of knee osteoarthritis (OA), with a specific focus on improving hamstring flexibility and reducing functional …
Sponsor: Khyber Medical University Peshawar • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Grapes vs. stress: can a snack shield your brain?
Symptom relief Recruiting nowThe main aim of the current study is to investigate whether consuming grapes rich in flavonoids just before mental stress can protect cerebrovascular and peripheral vascular function, mood and cognition, from the negative effects of mental stress in young healthy adults. A second…
Sponsor: University of Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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COPD inhaler showdown: which triple therapy wins?
Disease control CompletedThe goal of this clinical trial is to determine if triple inhaled therapy with Budesonide/Glycopyrronium/Formoterol (BGF) and Fluticasone Furoate/Umeclidinium/Vilanterol (FUV) are effective in treating patients with stable chronic obstructive pulmonary disease (COPD). It will als…
Phase 4 • Sponsor: Thammasat University • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Could an apple a day keep allergy symptoms away?
Symptom relief CompletedThis study was conducted to see before and after treatment whether it provided improvement in the patient's clinical symptoms.
Sponsor: Universitas Sebelas Maret • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Brain study could pave way for new stroke therapies
Knowledge-focused By invitation onlyNeural diseases such as stroke can have distinct effects on the ability to navigate and orient compared to remembering daily events like when one last took medicine. This proposal seeks test rival hypotheses regarding the neural mechanisms underlying commonalities and differences…
Early phase 1 • Sponsor: University of Arizona • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Your DNA could determine how well anesthesia works
Knowledge-focused OngoingThis study investigates the influence of genetic polymorphisms in key drug-metabolizing enzymes-CYP2B6, CYP2C9, and UGT1A9-on the individual response to propofol, a widely used intravenous anesthetic, in patients undergoing general anesthesia. Despite propofol's fast onset and fa…
Sponsor: Superior University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Blood test may predict who loses dangerous belly fat after surgery
Knowledge-focused CompletedThis study aims to investigate whether a specific protein in the blood, called resistin, can help doctors predict how much dangerous internal fat a patient will lose following weight loss surgery. Sleeve gastrectomy is a common and effective procedure that reduces the stomach's s…
Sponsor: Sercan YUKSEL, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Gentle neck moves may ease tennis Players' pain
Symptom relief CompletedThis prospective, single-blind, parallel-group randomized controlled trial evaluated whether adding cervical and thoracic spinal mobilization (Maitland concept, grades I-IV) to a structured home therapeutic exercise program improves pain intensity and physical fitness parameters …
Sponsor: Istinye University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Gum graft boosts dental implant outcomes in small study
Disease control CompletedTo evaluate soft tissue augmentation using acellular dermal matrix (ADM) over immediately placed dental implants in anterior maxilla.
Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Could your gut and kidneys be affecting your brain? new MRI study investigates
Knowledge-focused CompletedIgA nephropathy (IgAN) is the most common primary glomerular disease worldwide. Its progression is often accompanied by cognitive decline, manifesting as multi-dimensional cognitive deficits in areas such as memory, attention, and executive function. Cognitive decline in patients…
Sponsor: Tang-Du Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Short therapy boosts student mental health
Symptom relief CompletedThe goal of this clinical trial is to evaluate the effects of a brief Acceptance and Commitment Therapy (ACT)-based group intervention on psychological flexibility, values-based functioning, and psychological well-being in university students aged 18 to 28 years presenting elevat…
Sponsor: Universidad del Valle, Colombia • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New 3D-Printed brace aims to make scoliosis treatment less painful for teens
Symptom relief Recruiting nowScoliosis bracing is an effective treatment method for idiopathic scoliosis, but only if worn consistently for many hours a day. Unsurprisingly, brace discomfort is a significant deterrent against treatment adherence. For decades, custom braces for idiopathic scoliosis have been …
Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Heart function checked before and after lung removal
Knowledge-focused CompletedLung resection is associated with high postoperative morbidity and mortality and leads to a significant long-term decrease in functional capacity, particularly due to cardiorespiratory complications. One of the contributing factors to this functional decline is the postoperative …
Sponsor: Çağrı Özdemir • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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A video before the first feed: could a short animation boost breastfeeding attitudes in new moms?
Knowledge-focused CompletedThe purpose of this randomized controlled study is to evaluate the effect of video-based breastfeeding education on infant feeding attitudes among primiparous mothers who delivered by cesarean section or vaginal birth. Breastfeeding education may improve mothers' knowledge and at…
Sponsor: Zonguldak Bulent Ecevit University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC