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127005 trials found · Page 4461 of 6351
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Can a simple activity monitor improve rehab for older patients?
Knowledge-focused CompletedStaying active is essential for healthy aging, but hospitalized older adults in rehabilitation often move very little. This study explores how much physical activity these patients actually get and how it relates to their recovery. Using the MOX activity monitor-a device that acc…
Sponsor: KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Obesity drug study ends early, but Real-World data may still help
Disease control Stopped earlyParticipants will be treated with commercially available semaglutide according to routine clinical practice at the discretion of the treating physician for the management of obesity. The purpose of this study is to collect data on the effect of Semaglutide under everyday conditio…
Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New study reveals hidden costs of premature baby care
Knowledge-focused Recruiting nowPREM-IMPACT is a UK-based observational study exploring how caring for a very premature baby-particularly one affected by necrotising enterocolitis (NEC)-impacts families over the first year after hospital discharge. NEC is a serious bowel disease that can occur in premature babi…
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New graft promises better healing after skin cancer removal
Disease control CompletedThe goal of this single-arm clinical trial is to learn about the effectiveness and safety of the X A-DERM™ mADM in promoting wound healing and improving scar formation after MMS surgery for removing BCC, SCC, or MIS lesions on the face, head, and upper limbs. The main questions i…
Sponsor: McGuire Institute • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Eye ultrasound may spot spinal headache risk
Diagnosis CompletedThis study aims to investigate the hypothesis that ultrasonographic optic nerve sheath diameter (ONSD) measurement can help predict the development and severity of postdural puncture headache (PDPH) in patients undergoing spinal anesthesia for total knee arthroplasty. PDPH is def…
Sponsor: Ankara City Hospital Bilkent • Aim: Diagnosis
Last updated Jun 27, 2026 09:04 UTC
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One sleepless night may reveal early Alzheimer's clues in young adults
Knowledge-focused Recruiting nowThis study aims to investigate the effects of 24-hour acute sleep deprivation on plasma Alzheimer's disease biomarkers and multi-omics in individuals with different APOE genotypes, to elucidate the potential role of acute sleep deprivation in AD risk.
Sponsor: Yuhui Qiu • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Smart socks track Parkinson's gait in new study
Knowledge-focused Recruiting nowThis observational study aims to explore the use of the DANU Smart Socks for gait and balance assessment in people with Parkinson's (PwP). The study will compare walking and balance outcomes produced by DANU from people with Parkinson's (PwP) and a group of healthy individuals of…
Sponsor: Northumbria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can smart socks predict falls in Parkinson's patients?
Knowledge-focused Recruiting nowThe main objective of this observational trial is to explore the validity and reliability of DANU smart socks when used for mobility assessments in people with Parkinson's. Using a series of laboratory gold standard equipment, this project aims to compare the metrics observed by …
Sponsor: Northumbria University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can microneedling with a chemo drug restore skin color in vitiligo?
Disease control Recruiting nowThe goal of this clinical trial is to learn how well 5 fluorouracil (5FU) with micro-needling works to treat limited vitiligo as compared to strong steroid applied on skin. It will also learn about the safety of both these treatments. The main questions it aims to answer are: * …
Early phase 1 • Sponsor: Combined Military Hospital (CMH) institute of Medical Sciences Bahawalpur Pakistan • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New online program aims to ease cancer treatment side effects
Symptom relief CompletedThis study was designed to develop and evaluate the effectiveness of a web-based supportive care program for individuals diagnosed with colorectal cancer undergoing cancer treatment. The program's effectiveness is evaluated based on the symptom burden and quality of life experien…
Sponsor: Ilknur Yazicioglu • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New way to detect pain in tiny babies on ventilators
Knowledge-focused Recruiting nowThe goal of this observational study is to learn more about the pain and stress experienced by newborn infants receiving mechanical ventilation (breathing through a machine). The main questions it aims to answer are: * Do different ventilator settings (modi) cause different deg…
Sponsor: Uppsala University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Do clear aligners shed microplastics? new study investigates
Knowledge-focused Recruiting nowAn observational longitudinal study measuring microplastic exposure and physiologic uptake in orthodontic patients receiving clear aligner treatment.
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:59 UTC
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New study asks: can health improve without focusing on weight?
Symptom relief OngoingThe WIN intervention aims to improve the mental, social and physical health as well as quality of life of participants with BMI≥30 without focusing on their weight, and with no aim of weight loss. The WIN 6 months intervention is based on the principles and methods of the weight …
Sponsor: Carsten Dirksen • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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CAR-T therapy for autoimmune diseases: study withdrawn before starting
Disease control CancelledThis study is a single-arm, single-center Investigator-Initiated Trial (IIT) designed to evaluate the safety, pharmacokinetic profile, and preliminary efficacy of CD19-BCMA CAR-T cells in subjects diagnosed with connective tissue diseases.
Sponsor: Guangzhou Bio-gene Technology Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Sound waves to the brain: a new hope for addiction?
Knowledge-focused OngoingThe primary objective of this study is to assess the safety and feasibility of FUS neuromodulation in participants with OUD and/or other SUDs.
Sponsor: Manish Ranjan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Spinal zaps help scientists map nerve damage in kids with spina bifida
Knowledge-focused Recruiting nowA study to use transcutaneous spinal cord stimulation to characterize sensorimotor deficits in a pediatric population of individuals with spina bifida.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Strum away the pain: music therapy tested for chronic back ache
Symptom relief Recruiting nowThe goal of this clinical trial is to learn if active music-based intervention works to treat patients with chronic low back pain. The main questions it aims to answer are: 1. Does active music-based intervention improve cognitive function? 2. Does active music -based interventi…
Sponsor: Sharon Wang-Price • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Text message reminders boost cancer screening in younger adults
Knowledge-focused CompletedThe goal of this study is to learn if sending text message invitations increases participation in colorectal cancer screening among 45-49 year olds in Yingge District, New Taipei City. It will also assess the effectiveness of this method. The main questions it aims to answer are:…
Sponsor: Chang Gung University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scorpion sting secrets: home cures may worsen danger
Knowledge-focused CompletedScorpion stings are a common medical emergency in Mexico, particularly in the state of Jalisco. While antivenom is the standard treatment for scorpion envenomation, there is variability in how it is used, including differences in dosing strategies. In addition, many patients use …
Sponsor: University of Guadalajara • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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3D-Printed jaw expanders could make treatment easier for kids
Disease control OngoingThe goal of this clinical trial is to determine whether two types of rapid maxillary expansion (RME) appliances produce different outcomes in children. RME is a treatment utilized to expand a narrow upper jaw. This study will include children aged 8 to 10 years who need upper jaw…
Sponsor: Baskent University • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC