Browse
Explore conditions, clinical trials, and the organisations running them.
Never miss a new study
Get alerted when new trials match your condition
Sign up free to track the conditions you care about and get a personal digest when new trials appear.
By submitting, you agree to our Terms of use
127005 trials found · Page 4227 of 6351
-
Toothache showdown: lidocaine vs articaine – which numbing drug wins?
Symptom relief Not yet recruitingContext: Lidocaine and articaine are two of the most commonly used local anesthetics in dentistry. Lidocaine has often been the anesthetic of choice in clinical practice, but in clinical experience, articaine has proven to be more effective in controlling pain during dental proce…
Phase 4 • Sponsor: Universidad Austral de Chile • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
-
AI video calms nerves before knee surgery
Symptom relief CompletedThis prospective single-group study aims to evaluate the effect of preoperative artificial intelligence-based video education on anxiety, anesthesia preference, satisfaction, and knowledge level in patients undergoing arthroscopic lower extremity surgery.
Sponsor: Tokat Gaziosmanpasa University • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
-
Blood tests may predict flap complications in breast reconstruction
Knowledge-focused Recruiting nowBrief Summary This observational study will follow patients who undergo DIEP flap breast reconstruction to better understand a common surgical challenge called ischemia-reperfusion (I/R) injury. I/R injury can happen when a flap has a period without blood flow (ischemia) and then…
Sponsor: Hubei Cancer Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
-
Can a common blood pressure pill shield diabetic kidneys from contrast dye?
Disease control Not yet recruitingThe aim is to assess the benefit of low dose oral amlodipine in renal protection from contrast induced nephropathy in diabetic patients in intensive care unit
Early phase 1 • Sponsor: Minia University • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
-
New study eyes hidden developmental hurdles in hypothyroid infants
Knowledge-focused Recruiting nowA review of the literature has focused primarily on the cognitive and motor development of children with congenital hypothyroidism, but no studies on sensory processing skills have been found. Considering the age range of the groups studied, studies conducted in the early stages …
Sponsor: Nigde Omer Halisdemir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
-
Scientists track immune changes in 9 volunteers stranded on Sub-Antarctic island for a year
Knowledge-focused Recruiting nowLiving for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system. Scientists have observed that people in such isolated conditions often experience more infections and…
Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
-
Could a simple handgrip exercise beat walking for blood pressure?
Disease control Not yet recruitingThe goal of this clinical study is to compare the effectiveness of isometric handgrip exercise versus walking exercise in improving blood pressure among hypertensive patients. The main question is Which of two exercise (Isometric Handgrip Exercise versus Walking Exercise) will be…
Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
-
Your voice may reveal hidden airway risks before surgery
Knowledge-focused Recruiting now1. Study Purpose This research aims to develop a novel, non-invasive, and simple method to predict difficult intubation before surgery. The core idea is that the anatomy of a person's throat and mouth, which determines the ease of intubation, also uniquely shapes their voice. …
Sponsor: Shanghai Jiao Tong University Affiliated Sixth People's Hospital • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
-
Flickering glasses may help volleyball players with wobbly ankles
Symptom relief CompletedEffect of Stroboscopic Balance Training on Chronic Ankle Instability in Volleyball Players
Sponsor: Biruni University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
-
New study aims to improve monitoring of rheumatoid arthritis with simple blood tests and ultrasound
Knowledge-focused Not yet recruitingRheumatoid arthritis (RA) is a chronic autoimmune disease that affects about 1% of the world's population \[1\]. The disease is characterized by synovial membrane inflammation. The impact of RA on quality of life is significant, as it can lead to considerable disability, reduced …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
-
Simple nerve stretch could ease knee arthritis pain without drugs
Symptom relief Not yet recruitingBackground: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality. There is a limited knowledge about using femoral nerve mobilization in treating patients with arthritic changes. Obj…
Sponsor: Prince Sattam Bin Abdulaziz University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
-
Teens watch 5-Minute videos to fight depression stigma
Knowledge-focused Not yet recruitingDepression-related stigma is a major barrier to help-seeking among adolescents with depression. In China, few interventions specifically target stigma reduction in this population. This study aims to evaluate the effectiveness of a video-based psychoeducational intervention in re…
Sponsor: Jian-Jun Ou • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
-
Could a few needles ease your jaw pain?
Symptom relief Recruiting nowThis study aims to evaluate the effectiveness of dry needling in patients with functional temporomandibular pain syndrome by comparing standard rehabilitation therapy alone with therapy combined with dry needling to reduce pain, improve jaw function and enhance quality of life.
Sponsor: Palacky University • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
-
Can ultrasound spot early arthritis risk in spinal injury patients?
Knowledge-focused CompletedSpinal cord injury patients often present with musculoskeletal comorbidities, including osteoarthritis. Early detection of cartilage damage is important for preventing osteoarthritis progression. This study aims to compare the talar cartilage thicknesses of spinal cord injury pat…
Sponsor: Gaziosmanpasa Research and Education Hospital • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
-
Cool vapor may soothe Post-Surgery thirst and nausea
Symptom relief Not yet recruitingCold vapor application is considered a promising intervention with the potential to alleviate side effects associated with anesthesia and surgery in the postoperative period. This study aims to determine the effect of cold vapor inhalation on dyspnea, thirst, nausea, and physiolo…
Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
-
Scientists probe hidden link between lung disease and mental health
Knowledge-focused Not yet recruitingBronchiectasis is a common lung disease. Approximately 20-40% of patients with bronchiectasis experience comorbid anxiety and depression. Multiple studies have now demonstrated that anxiety and depression are associated with an increased risk of disease exacerbation in these indi…
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
-
Diet and supplement combo tested for PCOS relief
Disease control Not yet recruitingThis study will look at whether a reduced-calorie Mediterranean-style eating plan, together with a synbiotic supplement, can improve health measures and quality of life in women who have polycystic ovary syndrome (PCOS) and are overweight or have obesity. Participants will be ass…
Sponsor: Atlas University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
-
Knee replacement recovery gets a mental makeover: new nursing model tested
Symptom relief Not yet recruitingThe ABC-X model is a systematic intervention approach based on stress source analysis and adaptation theory. It emphasizes the dynamic interaction between stressors (A), coping resources (B), cognitive appraisal (C), and crisis outcomes (X). By systematically assessing patients' …
Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
-
Czech study seeks to uncover hidden reflux in kids
Knowledge-focused Recruiting nowThis study aims to determine the prevalence of symptomatic gastroesophageal reflux disease (GERD) in children aged 8-9 years and 12-13 years in the Czech Republic. Participants are recruited through schools and complete a web-based questionnaire assessing reflux-related symptoms.…
Sponsor: University Hospital, Motol • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
-
Probiotics and gum treatment: a surprising link?
Knowledge-focused CompletedMost previous studies have evaluated standardized probiotic regimens as adjuncts to NSPT (Ausenda et al., 2023; Hardan et al., 2022; Mauriello et al., 2025). Less is known about how real-world probiotic product use during periodontal care relates simultaneously to clinical outcom…
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC