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116076 trials found · Page 4057 of 5804
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Heart failure study seeks to decode fluid overload
Knowledge-focused Recruiting nowThe goal of this observational is to study the prevalence of distinct congestion phenotypes and study their association with response to therapy and outcomes in acute heart failure patients. The main question\[s\] it aims to answer \[is/are\]: * Primary objective: to study the p…
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:03 UTC
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Could a hidden neck problem cause hip fractures? new study investigates
Diagnosis Recruiting nowRecent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall. Identification and treatment of cervical myelopathy can help prevent falls and future fragility fractures. The purpose of this study…
Phase: NA • Sponsor: Indiana University • Aim: Diagnosis
Last updated Jun 27, 2026 12:38 UTC
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3,000 patients to help uncover why some hearts suffer after Non-Cardiac surgery
Knowledge-focused Recruiting nowMyocardial injury during non-cardiac surgery (PMI) affects up to 16% of high-risk patients and represents a significant burden on healthcare systems. An acute myocardial infarction is defined by a dynamic increase in cardiac troponin (cTn) above the 99th percentile and is accompa…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:22 UTC
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AI learns to spot tricky airways before surgery
Knowledge-focused CompletedThis prospective observational study aims to develop an artificial intelligence model that can automatically determine the Cormack-Lehane classification from video laryngoscopy images in patients undergoing elective surgery. It also aims to predict the risk of difficult intubatio…
Sponsor: Duzce University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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AI chatbot coaches seniors toward healthier lives
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate the acceptability and preliminary effectiveness of a smartphone-delivered AI-based chatbot in promoting healthy dietary behavior and physical activity participation among older adults.
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:26 UTC
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New study reveals hidden hormone clues in rare nerve disease
Knowledge-focused CompletedFriedreich's ataxia (FA) is a rare autosomal recessive disorder caused by GAA repeat expansion in the FXN gene, leading to impaired iron-sulfur (Fe-S) cluster biosynthesis and mitochondrial dysfunction. Fe-S clusters are essential for the function of several enzymes involved in s…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Blood test may predict who loses most weight after obesity surgery
Knowledge-focused OngoingThe study looks at whether a specific protein in the blood, called apolipoprotein, can predict how much weight a person might lose after sleeve gastrectomy, a surgery for people with severe obesity. We want to find a specific level of this protein that shows which patients are mo…
Sponsor: Yigit DUZKOYLU • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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School health program aims to stop childhood obesity in its tracks
Prevention CompletedChildhood obesity is one of the most serious public health challenges of the 21th century. The problem is global and is steadily affecting many low and middle income countries particularly in unbar settings. Although definition of obesity and overweight has changed over time, it …
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Prevention
Last updated Jun 27, 2026 08:08 UTC
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4,500-Patient study aims to predict heart and kidney risks
Knowledge-focused Recruiting nowPatients with Cardiovascular-kidney-metabolic syndrome (CKM) will be prospectively enrolled. We will conduct comprehensive analyses, including transcriptomics, proteomics, and metabolomics, using various types of samples such as plasma and whole blood. Adenosine stress echocardio…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Can exercise boost brain health in obesity? new study investigates
Knowledge-focused Recruiting nowCerebral blood flow (CBF) is essential for maintaining brain health and function, as it ensures delivery oxygen and nutrients necessary to support neuronal activity. Reduced CBF can impair the brain's ability to meet its metabolic demands, leading to deficits in cognitive ability…
Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Spit test may predict lung injury severity in kids
Knowledge-focused ENROLLING_BY_INVITATIONThe aim of this study is to determine the degree of agreement in cytokines level measured through BAL and those measured through salivary glands excretion. and to compare the validity of cytokines in BAL versus salivary secretion in predicting the stage of ARDS and disease outco…
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New pain block cocktail could cut opioid use after hip surgery
Symptom relief CompletedThe current study was done to evaluate the effect of adding dexamethasone and magnesium sulfate to bupivacaine as adjuvants in an ultrasound-guided erector spinae block for patients undergoing total hip arthroplasty (THA), and to assess their impact on the timing of the first req…
Phase: PHASE2 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Silver dressing may soothe radiation burns in breast cancer patients
Symptom relief CompletedPatients who are eligible to receive adjuvant whole breast radiotherapy with or without regional nodal irradiation as part of their care will be included in this study. Patients will use Silver-plated technology (SPT) dressing as directed per user instruction manual and change dr…
Phase: NA • Sponsor: Parul Barry • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Simple coaching may boost inhaler use in rare lung disease
Disease control Recruiting nowPulmonary Arterial Hypertension is a rare and progressive condition that compromises pulmonary circulation and can lead to right ventricular failure. Despite recent advances in diagnosis and treatment, the median survival of patients is only 2.8 years. The treatment for this dise…
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Lasers could make brace removal a breeze
Symptom relief OngoingThis randomized split-mouth clinical trial evaluates enamel surface preservation, pulpal temperature variation, and patient-reported discomfort during ceramic orthodontic bracket removal using two Erbium-doped yttrium aluminum garnet (Er:YAG) laser parameter settings compared to …
Phase: NA • Sponsor: Saint-Joseph University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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New hip surgery pain block could cut opioid use
Symptom relief CompletedIn this single-center retrospective study, patients who underwent hip surgery between May 2025 and November 2025, with American Society of Anesthesiology (ASA) physical status I-III, aged 18 years and older, were screened. Patients who did not undergo a block for postoperative an…
Phase: NA • Sponsor: Istanbul Medeniyet University • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Smoothie science: tiny greens, big iron hope for women
Disease control CompletedThe investigators present a pilot diet intervention study, to be conducted as a within-subject design, to assess the feasibility of iron biofortified microgreens on iron intake and status in women of reproductive age and postmenopausal women. This will be investigated by providin…
Phase: NA • Sponsor: University of Aberdeen • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Kindness training boosts breastfeeding confidence in new moms, small study finds
Symptom relief CompletedThis randomized controlled trial aims to evaluate the effects of compassion-based breastfeeding counseling on self-compassion, mindful breastfeeding, and breastfeeding self-efficacy during the perinatal period. Pregnant women between 24-28 weeks of gestation who meet the eligibi…
Phase: NA • Sponsor: Gazi University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Knee pain relief: targeted exercises show promise in small trial
Symptom relief OngoingPatellofemoral Pain (PFP) is one of the most common causes of knee pain and is significantly present in recreational athletes who have previously been categorized as being in a subgroup of PFP. Understanding which intervention is most appropriate for this subgroup could give us i…
Phase: NA • Sponsor: Universidade do Porto • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Austrian study seeks to eliminate hepatitis by linking patients to care
Knowledge-focused Recruiting nowThe HEAL-S study is a non-interventional study with retrospective data analysis. It consists of two parts. First a retrospective analysis based on nucleic acid testing (NAT) results will be performed. Two cohorts (HCV) and (HBV) will be established. Patients falling into one (or …
Sponsor: Vanessa Stadlbauer-Koellner, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC