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127005 trials found · Page 3706 of 6351
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Zapping buttock muscles may improve sitting for spinal injury patients
Symptom relief CompletedThe aim of the study is to investigate whether there is an effect of electrical stimulation on the denervated gluteus muscle (buttocks) in individuals with chronic spinal cord injury. The expected outcome is an increase in muscle volume and a better pressure distribution during s…
Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New ultrasound technique could ease carpal tunnel pain without major surgery
Symptom relief CompletedThe objective of the study is to evaluate in patients suffering from carpal tunnel syndrome resistant to medical treatment, clinical course after percutaneous treatment under ultrasound guidance. 40 patients will be included in the study. The following parameters will be evaluate…
Phase 2 • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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New tool helps parents of diabetic tots tame blood sugar
Disease control CompletedDIAB-EDUC tests in a group of young diabetic patients (less than 6 years old) a specific educational tool in order to assess its impact on glycemic control, quality of life, knowledge about the disease and its daily management, over a period of 2 years. The investigators plan to …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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MRI heart scan may forecast future for heart muscle disease patients
Knowledge-focused Completed: Fibrosis, in general, is a scarring process, which is characterized by fibroblast accumulation and excess deposition of extracellular matrix (ECM) proteins, which leads to distorted organ architecture and function. The contribution of fibrogenesis to impaired cardiac function i…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis phase I trial studies the side effects and the best dose of veliparib and dinaciclib in treating patients with solid tumors that have spread to other places in the body and usually cannot be cured or controlled with treatment. Veliparib and dinaciclib may stop the growth of …
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Can vitamin d tweak breast cancer genes? weight may matter
Disease control Stopped earlyThis is a research study of the effect of Vitamin D on breast cancer. We hope to learn whether Vitamin D can change characteristics of certain genes in a breast cancer tumor that affect its growth. We believe some of these characteristics may be influenced by body weight.
Phase 2 • Sponsor: Melinda Telli • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Heart MRI may reveal who really needs a shock device
Knowledge-focused CompletedDelayed enhanced MRI in patients (of either ischemic or non-ischemic cause) being referred for primary prevention ICD
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Job support program shows promise for mental health recovery
Knowledge-focused CompletedThe aim of the present study, is to evaluate the effect of a supported employment intervention, IPS-modified for people with mood and anxiety (IPS-MA) on employment or education, when offered to people with onset mood or anxiety disorders who are not likely to be able to return t…
Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Breathing exercise boosts rehab for COPD patients
Symptom relief CompletedThe purpose of this study is to determinate whether inspiratory muscle training (IMT) associated with a conventional respiratory rehabilitation program is more effective than a conventional respiratory rehabilitation program alone,on Dyspnea in chronic obstructive pulmonary disea…
Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Brain zaps curb smoking cravings in hardcore nicotine addicts
Symptom relief CompletedThe fight against smoking is a public health priority. Without help, fewer than 5% of des smokers are abstinent at 12 months after smoking cessation. Despite well-managed attempts at smoking cessation with nicotine substitutes, the rate of success at 12 months in patients depend…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Hearing loss pill shows promise in early trial
Prevention CompletedExposure to loud sounds can cause hearing loss. The purpose of this research study is to evaluate potential prevention of temporary changes in hearing that may occur after listening to music through an iPod or personal music player. We will measure temporary changes in hearing in…
Phase 2 • Sponsor: Sound Pharmaceuticals, Incorporated • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Can a short workout before breast cancer surgery change tumor markers?
Knowledge-focused OngoingThis study is designed to look at the changes that occur in women who take part in exercise and Mind-Body programs between breast cancer diagnosis and breast surgery. The investigators will look at changes in stress, anxiety, mood and quality of life, to see if these types of sho…
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Blood tests may replace scopes for EoE diagnosis
Knowledge-focused CompletedPurpose: To validate our previously developed model of risk factors for diagnosis of eosinophilic esophagitis (EoE), and to assess the utility of serum levels of biomarkers in diagnosis and monitoring of treatment of EoE. Participants: Up to a total of 800 participants (approxima…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Can a survey capture what patients expect from thyroid surgery?
Knowledge-focused OngoingThe purpose of this study is to learn more about what patients undergoing surgery for thyroid cancer expect from their surgery. Your input may help us to better prepare and inform patients about their disease and its treatment.
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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Global registry launches to unlock secrets of rare wolfram syndrome
Knowledge-focused Recruiting nowIn this study, the investigators hypothesize that studying monogenic variants with strong effect associated with severe insulin deficiency of Wolfram syndrome will provide important insights into the more complex type 1 and type 2 diabetes mellitus. Aim 1. Establish and maintain…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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8,000-Patient study aims to perfect Scope-Based cancer prevention
Knowledge-focused Recruiting nowTo evaluate clinical outcome for patients receiving treatment of suspected premalignant and malignant gastrointestinal lesions at Interventional Endoscopy Services. The primary outcome is curative endoscopic resection. Secondary outcomes include resection technique utilized, rate…
Sponsor: California Pacific Medical Center Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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15-Minute iron shot could beat anemia fast
Disease control CompletedThe aim of the study is to recruit 30 patients who have been referred to Auerach Hematology Oncology Assoc. for the treatment of iron defeciency anemia with iv iron (Ferumoxytol 1020 mg) administered via infusion pump over 15 minutes. To ascertain acute safety and tolerability o…
Sponsor: Auerbach Hematology Oncology Associates P C • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Hepatitis b drug holiday: study tests if stopping pills is safe
Knowledge-focused CompletedBackground: \- Chronic infection with the hepatitis B virus may lead to cirrhosis, liver disease, and cancer of the liver. There is no cure for the infection, but several drugs have been approved to treat it. These drugs can keep the virus levels low. They seem to be safe for sh…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Scientists scan teen brains to unlock secrets of eating disorders
Knowledge-focused PausedCurrently, there is not a robust, testable neural model available that sufficiently explains the development and maintenance of anorexia nervosa (AN) a severe, often fatal, adolescent-onset eating disorder. Using state of the art neuroimaging and neuropsychological techniques, ou…
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Obesity surgery as a day procedure? small study tests feasibility
Symptom relief CompletedThe aim of this study is to determinate the feasibility of the Laparoscopic Sleeve Gastrectomy, a bariatric surgery i.e. a surgery as a treatment for obesity, could be proposed as a Day-Case surgery.
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 26, 2026 19:06 UTC