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127005 trials found · Page 3654 of 6351
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Brain training games put to the test for TBI recovery
Knowledge-focused Recruiting nowThis project will examine if computerized cognitive remediation will improve working memory and attention in 25 adults with a mild, moderate, or severe brain injury and compare their cognitive performance to the control group of 25 adults with a mild, moderate, or severe brain in…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Glowing dye helps surgeons see hidden liver tumors in real time
Knowledge-focused CompletedAchievement of tumor-free resection margin with the largest possible remnant liver parenchyma is the major challenge in hepatic surgery. Therefore, perioperative tumor detection, anatomical mapping of liver segments and also nearby structures are vital to improve the short- and l…
Sponsor: Klinikum Saarbrücken, Klinik für Allgemein-, Viszeral- und Thoraxchirurgie, Chirurgische Onkologie • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:32 UTC
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Blenderized diets may ease reflux in Tube-Fed kids
Knowledge-focused Recruiting nowBlenderized diets consist of a wide range of table foods such as fruits, vegetables, meat and legumes, pureed in a blender and administered via gastrostomy tube. In a recent study, the investigators reported that children receiving blenderized feeds via gastrostomy had fewer tota…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Cooling newborns: what happens to their hearts?
Knowledge-focused CompletedPerinatal hypoxia in the form of hypoxic-ischaemic encephalopathy (HIE) is a frequent cause of cerebral impairment in neonates. HIE occurs in 3 to 5 of 1000 neonates in developed countries and is significantly higher in developing countries at 25 of 1000 neonates. Despite develop…
Sponsor: Princess Anna Mazowiecka Hospital, Warsaw, Poland • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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AI-Powered detectors aim to prevent errors in nuclear medicine
Knowledge-focused Recruiting nowThe study aims to identify and predict radiopharmaceutical extravasation events using new semi-quantitative parameters and machine learning models. It involves dose rate measurements to develop metrics for real-time monitoring. It also investigates the correlation between extrava…
Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Kidney stone showdown: which treatment leaves patients happier?
Symptom relief CompletedThe purpose of this study is to determine the differences in stone free results, patient side effects, and patient satisfaction between dusting vs. basket extraction for kidney and ureteral stones (a kidney stone located in the tube between the kidney and bladder) 6 mm and greate…
Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
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New study aims to improve surgery for twisted spines
Knowledge-focused Recruiting nowEvaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revi…
Sponsor: International Spine Study Group Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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10-Year checkup: do these shoulder implants hold up?
Disease control Recruiting nowThe objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiog…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Nasal clues could unlock new asthma attack treatment
Knowledge-focused CompletedTo study the change from baseline in IL-1β (interleukin 1 beta) concentrations in the nasal airway during acute asthma exacerbation, specifically to measure the degree of change and identify the timing of peak IL-1β concentration. This information will allow the investigators to …
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Could a High-Tech insulin system and Low-Carb diet fix a dangerous diabetes problem?
Knowledge-focused CompletedAlmost all people who have had type 1 diabetes for 5 years have a defect in secretion of the hormone Glucagon. This hormone is involved in the body's response to low blood glucose (hypoglycaemia). It works by releasing glucose stores from the liver to bring the blood glucose back…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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E-Cig users show early signs of harm: new study investigates
Knowledge-focused OngoingThis study examines how electronic (e)-cigarette use impacts the body, by studying both users and non-users of e-cigarettes. Early evidence indicates that e-cig users experience adverse health effects. Results of this study may help policy-makers develop standards for different t…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Probiotic shows promise for constipation relief
Symptom relief CompletedThe investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Bacillus coagulans on various symptoms and fecal microbial diversity in adults with with functional constipation for 12 weeks.
Sponsor: Pusan National University Yangsan Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Stroke vision loss: brain training shows promise in new study
Knowledge-focused OngoingThis research aims to examine changes in plastic potential of the visual system with time from stroke affecting primary visual cortex. We will measure structural and mechanistic aspects of progressive degeneration along the early visual pathways, correlating them with changes in …
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New biomarkers may spot kidney trouble after heart surgery
Knowledge-focused CompletedThe aim of this study was to identify and validate novel biomarkers including functional tests for detecting AKI, AKI progression and other poor outcomes.
Sponsor: Guowei Tu • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New program helps smokers with mental illness kick the habit
Disease control CompletedTobacco use disorder is a chronic disease. This is particularly true for people living with mental illness, who are more likely to smoke and make more unsuccessful quit attempts than those without. The current study is designed to test a package of two chronic disease management …
Phase 2 • Sponsor: Sandra Japuntich • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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New blood tests could spare transplant patients from painful biopsies
Knowledge-focused CompletedThis is a non-randomized, non-interventional, prospective pilot cohort study to monitor SPK patients post-transplant to determine if non-invasive measures using dd-cfDNA (Allosure) and AlloMap can assess an array of immune panels to predict and confirm the development of allograf…
Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Virtual reality hypnosis tested for sickle cell pain in kids
Symptom relief CompletedThe purpose of this study is to evaluate the effect of Virtual Reality induced Hypnosis on patients' pain scores, anxiety and the use of analgesics during a vaso-occlusive crisis
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 17:37 UTC
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1,000 patients join hunt for stomach cancer early warning signs
Knowledge-focused By invitation onlyThe UC Davis Cohort of Pre-Malignant and Malignant GastroIntestinal DisEases (TUMMIE) Study is a prospective longitudinal cohort study designed to improve understanding of the natural history, risk factors, and biological mechanisms underlying gastric pre-malignant conditions and…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Brain study aims to improve speech therapy for stroke survivors
Knowledge-focused Recruiting nowAphasia is the most common type of post-stroke communication disorder characterized by deficits in speech comprehension, production and control. While recovery can be promoted with speech therapy, improvement remains modest and typically requires a large number of sessions contri…
Sponsor: The University of Texas at Dallas • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Tuning in: study tests if deeper cochlear implant settings boost music enjoyment
Symptom relief Recruiting nowMain objective: Investigate on new cochlear implanted patients whether the FineHearing strategy of the MED-EL cochlear implant gives better results on musical perception if the depth of stimulation (stimulation or not of the apical areas) is greater. Secondary objectives: Eval…
Sponsor: MED-EL Elektromedizinische Geräte GesmbH • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC