Probiotic shows promise for constipation relief

NCT ID NCT04997187

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a daily probiotic supplement called Bacillus coagulans could improve constipation symptoms and gut bacteria in adults. Eighty participants took either the probiotic or a placebo for 12 weeks. The goal was to see if the probiotic could ease discomfort and improve stool consistency.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bacillus coagulans (a probiotic supplement)

What this could lead to

If it works, this could offer a natural, over-the-counter option to help relieve constipation without harsh laxatives.

What could go wrong

This is a small, completed trial with only 80 participants. The results may not apply to everyone, and probiotics can cause bloating or gas in some people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

constipation disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pusan National University Yangsan Hospital

    Yangsan, Gyeungsangnam-do, 50612, South Korea