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Super maize? study checks if biofortified corn boosts nutrient absorption in guatemalan children

NCT ID NCT06650397

Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether biofortified maize—corn grown to have higher zinc and iron—helps school-aged children in Guatemala absorb more of these nutrients compared to traditional maize. Fifty-six children aged 10-14 ate tortillas made from either biofortified or regular maize for 27 days. Researchers used stable isotopes to measure how much zinc and iron their bodies actually absorbed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
biofortified maize
What this could lead to
If successful, this could show that biofortified maize is a better source of zinc and iron than traditional maize, potentially helping reduce nutrient deficiencies in regions where maize is a staple food.
What could go wrong
This is a small, completed study with only 56 children in a specific region, so results may not apply broadly. It measures absorption, not long-term health outcomes, so real-world benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Jul 2024

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 14 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * 10-14 years old school children (male and female sex) * BMI between10-85%tile * Typically eat homemade tortillas at each meal every day Exclusion criteria: * Taking iron or zinc supplements * Hemoglobin less than 12.9 g/dl for children 10-11 yrs old and less than13.4 g/dl for children 12-14 yrs old (Per the WHO's 2024 publication hemoglobin cut-offs for identifying anemia are 5-11 yrs: less than 11.5 g/dl; 12-14 yrs: less than 12.0 g/dl. To adjust for the elevation of Tecpán at 2254 m, 1.4 g/dl is added to the cut-off point.) * Girls who are having a menstrual period during the metabolic studies

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Conditions

The condition(s) this trial relates to.

Callosities

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Iron absorption Zinc absorption

Contacts and locations

Locations

  • Institute of Nutrition of Central America and Panama

    Guatemala City, Departamento de Guatemala, 1188, Guatemala

More trials for these conditions

Other studies related to the condition(s) this trial covers.