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Can writing about trauma reduce PTSD and cravings in addiction treatment?

NCT ID NCT07397507

Knowledge-focused Sponsor: Mclean Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a brief writing therapy called Written Exposure Therapy (WET) works for people with both PTSD and substance use disorders who are in residential treatment. About 108 participants will either do WET or neutral writing alongside their usual care. Researchers will measure PTSD symptoms, substance use, and physical responses like heart rate and cravings to trauma cues, and also explore how sex hormones may affect these changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 108 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Mar 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. ability to understand and sign informed consent 2. ability to write in English; 3. age between 18-55 (average age of menopause in the US) 4. \[women only\] naturally cycling (i.e., regular cycles, not on gonadal-related hormones) 5. current diagnosis of a moderate or severe DSM-5 SUD 6. current diagnosis of DSM-5 PTSD 7. sufficient memory of the trauma to write about the event 8. at least 5 business days left in their residential treatment episode (to allow for 5 treatment sessions). Exclusion Criteria: 1. presence of a psychiatric or medical condition that would interfere with participation (e.g., severe, uncontrolled psychosis) 2. prescription of a PRN benzodiazepine 3. current PTSD treatment

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Conditions

The condition(s) this trial relates to.

combat disorder post-traumatic stress disorder substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PTSD - post traumatic stress disorder Substance use disorder (SUD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.