New stitch method aims to cut infection risk after appendix removal
NCT ID NCT07274878
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will compare two methods of closing the skin after open appendix surgery: standard interrupted stitches versus a continuous stitch under the skin plus a small drain. The goal is to see which method leads to fewer wound infections and better healing. About 100 people aged 14 and older will take part.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- subcuticular suture plus subcutaneous drain
- What this could lead to
- If this works, it could point toward a better way to close wounds after open appendectomy, reducing infections and improving scar appearance.
- What could go wrong
- This is a small, early-stage trial with only 100 participants, so results may not apply to everyone. The drain could cause its own complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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14 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 14 years (or per local ethics), undergoing open appendectomy for acute appendicitis (elective not included). * Skin incision for open appendectomy (McBurney/Gridiron or Lanz). * Patient (or legal guardian) able and willing to provide informed consent. Exclusion Criteria: * Laparoscopic appendectomy or conversion to laparoscopic approach. * Previous abdominal surgery at the same site (risk of altered wound healing). * Pre-existing skin infection at the surgical site.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which surgery for appendicitis has fewer complications?
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