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Blood test may spot appendicitis faster, study finds

NCT ID NCT07643142

Diagnosis Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether measuring a protein called calprotectin in the blood can help diagnose acute appendicitis. Researchers compared 74 patients with abdominal pain, some with confirmed appendicitis and others with non-specific pain. They measured calprotectin levels and compared them to standard tests to see if it could improve diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Serum calprotectin measurement (blood test)
What this could lead to
If successful, this blood test could help doctors diagnose acute appendicitis faster and more accurately, reducing unnecessary surgeries.
What could go wrong
This is a small, completed study with only 74 participants. Larger studies are needed to confirm if the test is reliable enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

74 people

The number who actually took part.

Started

Dec 2015

Finished

Apr 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients presenting to the emergency department with acute abdominal pain and suspected acute appendicitis. Participants were divided into two groups: patients diagnosed with acute appendicitis and patients with non-specific abdominal pain.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 75 years * Presentation to the emergency department with acute abdominal pain and suspected acute appendicitis * Willingness to participate and provide informed consent Exclusion Criteria: * Previous abdominal surgery * Chronic inflammatory or autoimmune disease * Active infection other than suspected appendicitis * Use of systemic anti-inflammatory or immunosuppressive therapy * Pregnancy * Incomplete clinical or laboratory data

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Conditions

The condition(s) this trial relates to.

Abdominal Pain appendicitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal pain Acute appendicitis

Contacts and locations

Locations

  • Fatih Sultan Mehmet Training and Research Hospital

    Istanbul, ATASEHIR, 34752, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.