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Keyhole vs open surgery: which appendectomy works better for obese patients?

NCT ID NCT07822503

Symptom relief Sponsor: University of Health Sciences Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers compare two surgical methods for removing an inflamed appendix in obese patients: laparoscopic (keyhole) surgery and traditional open surgery. The trial enrolls 166 obese adults with acute appendicitis, randomly assigning each to one of the two procedures. The main goals are to see which approach leads to fewer surgical site infections and shorter hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Laparoscopic appendectomy and open appendectomy surgical procedures
What this could lead to
If laparoscopic surgery proves better for obese patients, it could become the preferred approach, reducing infections and shortening hospital stays.
What could go wrong
This is a single-center study with 166 participants, so results may not apply everywhere. Surgical risks exist for both procedures, and outcomes can vary by surgeon skill and patient factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 166 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Obese patients with Body Mass Index (BMI) ≥ 30 kg/m². 2. Clinical diagnosis of acute appendicitis based on Alvarado score (history of right lower quadrant or periumbilical pain shifting to RLQ, nausea and/or vomiting, fever \> 38 °C, RLQ guarding and tenderness, and/or leukocytosis \> 10,000 cells/mL). 3. Age between 15 and 50 years. 4. Both male and female patients. Exclusion Criteria: 1. Immunocompromised patients (e.g., HIV infection or current steroid therapy). 2. History of prior chemotherapy, radiotherapy, or recurrent infections. 3. History of drug or alcohol abuse. 4. Severe hepatic, renal, or cardiovascular dysfunction. 5. History of previous abdominal surgery. 6. Appendicular malignancy. 7. Pregnant women. 8. Preoperative findings indicating appendiceal perforation.

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Conditions

The condition(s) this trial relates to.

appendicitis disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute appendicitis Appendicitis (diagnosis) Obesity

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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More trials for these conditions

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