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New mRNA shot takes aim at stubborn autoimmune diseases

NCT ID NCT07349823

First seen Feb 01, 2026 · Last updated May 21, 2026 · Updated 10 times

Summary

This early-phase study tests a new drug called WGb-0301 for people with autoimmune diseases (like lupus or autoimmune hepatitis) that have not responded to standard treatments. The drug uses mRNA technology to target and clear certain immune cells (B cells) that are causing the disease. The main goals are to find a safe dose and see if it can control the disease long-term. About 47 adults aged 18-70 will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

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