New drug combo aims to stop weight regain in severely obese teens
NCT ID NCT04298203
First seen Apr 10, 2026 · Last updated May 15, 2026 · Updated 4 times
Summary
This study tests whether a combination of two drugs, phentermine and topiramate, can help teens aged 12 to 18 with severe obesity maintain weight loss after a meal replacement program. The body often fights weight loss by increasing appetite and slowing metabolism, making it hard to keep weight off. The study will also check the drugs' safety, including effects on heart, bones, and thinking. About 100 teens will participate, and the results could offer a new option for long-term weight management.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Minnesota
Minneapolis, Minnesota, 55455, United States
Conditions
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