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New needle treatment could replace surgery for curable high blood pressure

NCT ID NCT05405101

First seen Feb 26, 2026 · Last updated May 20, 2026 · Updated 12 times

Summary

This study tests if a less invasive needle-based treatment (thermal ablation) works as well as surgery to cure a specific type of high blood pressure called primary aldosteronism. About 122 adults with this condition will be randomly assigned to one of the two treatments. The goal is to see if the needle treatment can normalize blood pressure and potassium levels without the need for lifelong medication, offering a faster recovery and fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cambridge University Hospitals NHS Foundation Trust

    RECRUITING

    Cambridge, SMLG, CB2 0QQ, United Kingdom

    Contact Email: •••••@•••••

  • Guy's and St Thomas' NHS Foundation Trust

    RECRUITING

    London, SE1 9RT, United Kingdom

    Contact Email: •••••@•••••

  • Imperial College Healthcare NHS Trust

    RECRUITING

    London, W12 0HS, United Kingdom

    Contact Email: •••••@•••••

  • Sheffield Teaching Hospitals NHS Foundation Trust

    RECRUITING

    Sheffield, S10 2JF, United Kingdom

    Contact Email: •••••@•••••

  • St Bartholomew's Hospital

    RECRUITING

    London, EC1A 7BE, United Kingdom

    Contact Email: •••••@•••••

  • University College London Hospital NHS Foundation Trust

    RECRUITING

    London, NW1 2PG, United Kingdom

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.