New needle treatment could replace surgery for Hormone-Driven high blood pressure
NCT ID NCT05405101
First seen Feb 26, 2026 · Last updated May 15, 2026 · Updated 11 times
Summary
This study tests if a less invasive procedure called thermal ablation (using heat from a needle) works as well as surgery to cure primary aldosteronism, a condition where a small adrenal gland tumor causes high blood pressure. About 122 adults with a tumor in one adrenal gland will be randomly assigned to either ablation or keyhole surgery. The goal is to see if ablation can normalize blood pressure and hormone levels without the need for lifelong medication, while also reducing hospital stays and speeding up recovery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cambridge University Hospitals NHS Foundation Trust
RECRUITINGCambridge, SMLG, CB2 0QQ, United Kingdom
Contact Email: •••••@•••••
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Guy's and St Thomas' NHS Foundation Trust
RECRUITINGLondon, SE1 9RT, United Kingdom
Contact Email: •••••@•••••
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Imperial College Healthcare NHS Trust
RECRUITINGLondon, W12 0HS, United Kingdom
Contact Email: •••••@•••••
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Sheffield Teaching Hospitals NHS Foundation Trust
RECRUITINGSheffield, S10 2JF, United Kingdom
Contact Email: •••••@•••••
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St Bartholomew's Hospital
RECRUITINGLondon, EC1A 7BE, United Kingdom
Contact Email: •••••@•••••
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University College London Hospital NHS Foundation Trust
RECRUITINGLondon, NW1 2PG, United Kingdom
Contact Email: •••••@•••••
Conditions
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