New needle treatment could replace surgery for curing Hormone-Driven high blood pressure

NCT ID NCT05405101

Ongoing ⭐️ CURE ⭐️ Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests if a less invasive needle-based treatment (thermal ablation) works as well as surgery to cure a hormone disorder called primary aldosteronism, which causes high blood pressure. About 122 adults with the condition will be randomly assigned to one of the two treatments. The goal is to see if the needle treatment can normalize blood pressure and hormone levels without the need for long-term medication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY ALDOSTERONISM are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRIMARY ALDOSTERONISM

Contacts and locations

Locations

Cambridge University Hospitals NHS Foundation Trust

Cambridge, SMLG, CB2 0QQ, United Kingdom
Guy's and St Thomas' NHS Foundation Trust

London, SE1 9RT, United Kingdom
Imperial College Healthcare NHS Trust

London, W12 0HS, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Sheffield, S10 2JF, United Kingdom
St Bartholomew's Hospital

London, EC1A 7BE, United Kingdom
University College London Hospital NHS Foundation Trust

London, NW1 2PG, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.