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Can a VR vacation lift depression in dialysis patients?

NCT ID NCT05642364

Symptom relief Sponsor: University of Illinois at Urbana-Champaign Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a 5-week virtual reality program that teaches positive thinking skills can help reduce depression and improve quality of life in people on hemodialysis. Sixty-one adults with end-stage kidney disease and mild-to-moderate depressive symptoms will either receive the immersive VR program or a placebo VR with nature scenes. The main goals are to see if the approach is feasible and acceptable, and to gather early data on its effects on mood, treatment adherence, and hospitalizations.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Virtual reality-based positive psychological intervention (Joviality™)
What this could lead to
If it works, this could offer a new, engaging way to improve emotional well-being and quality of life for people on dialysis.
What could go wrong
This is a small, early feasibility study with only 61 participants. It is designed to test whether the approach is acceptable and practical, not yet to prove it works. The control group also receives a VR experience, so any benefit may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

61 people

The number who actually took part.

Started

Jun 2023

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\) HD patient with at least three months since treatment initiation * 2\) Beck Depression Inventory-II (BDI-II) score ≥11 * 3\) age 21 or older * 4\) visual and audio acuity to immerse in our VR world * 5\) fluent in English or Spanish Exclusion Criteria: * 1\) unavailable for study period * 2\) prevalent cognitive impairment denoting dementia * 3\) physical limitation restricting use of a head-mounted display * 4\) history of epilepsy, seizures, or vertigo.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease Depression depressive disorder end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depressive symptoms End stage kidney disease

Contacts and locations

Locations

  • DaVita Garfield Kidney Center

    Chicago, Illinois, 60624, United States

  • DaVita Little Village Dialysis PD

    Chicago, Illinois, 60608, United States

  • UI Health - Dialysis Unit, EEI Suite 2028

    Chicago, Illinois, 60612, United States

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