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Vitamin c may change your gut bugs – new study

NCT ID NCT07388121

Knowledge-focused Sponsor: University of Glasgow Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how vitamin C supplements change the bacteria living in your gut. Twenty-three healthy adults will take a moderate dose (200 mg) and then a high dose (1000 mg) of vitamin C daily for two weeks each. Researchers will measure changes in gut bacteria, short-chain fatty acids, and inflammation markers from stool, blood, and urine samples.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vitamin C (ascorbic acid) as a dietary supplement
What this could lead to
If successful, this study could reveal how vitamin C influences gut health, potentially guiding future dietary recommendations.
What could go wrong
This is a small, early-stage study with only 23 healthy adults. Results may not apply to people with health conditions or different diets.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 23 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy individuals aged 18-65 years with a BMI between 18.5-35 Kg/m2 * Self-reported good health with no chronic conditions requiring regular medical care * Willing to provide blood, urine, and stool samples at multiple time points Exclusion Criteria: * Aged \<18 or \>65 years * Smoking * Chronic illness requiring regular medication or GP visits * Current or recent medication affecting gut transit or digestion * Major gastrointestinal surgery * Pregnant or breastfeeding * Regular use of pre/probiotics, vitamins, or minerals (unless willing to discontinue 2-4 weeks prior) * Antibiotics in past 3 months * Weight change \>±2 kg in past month * Participation in other research likely to interfere with this study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gut microbiota diversity and composition Short chain fatty acids concentration in stools

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • New Lister Building, Glasgow Royal Infirmary, 10-16 Alexandra Parade, G31 2ER

    RECRUITING

    Glasgow, G31 2ER, United Kingdom

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