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Butter vs. olive oil: which fat shapes your gut health?

NCT ID NCT07550023

Knowledge-focused Sponsor: University of Glasgow Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how adding a daily dose of butter, coconut oil, olive oil, or sunflower oil for two weeks changes the bacteria in your gut and related health markers. Healthy adults aged 20-50 will provide stool and blood samples to measure gut bacteria activity, blood fats, and inflammation. The goal is to understand which fats are better for gut health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 20-50 years * Body mass index (BMI) between 20 and 30 kg/m² * Generally healthy * Stable body weight (±2 kg) over the past 2 months * Living in the Glasgow area * Non-smoker Exclusion Criteria: * Use of antibiotics within the past 3 months * Current use of medications affecting gut microbiota or cardiometabolic health * Regular use of dietary supplements that may influence study outcomes (e.g. probiotics, prebiotics, vitamins, minerals, fish oil), unless willing to discontinue prior to study start * Presence of chronic gastrointestinal, metabolic, cardiovascular, hepatobiliary, or pancreatic disease * History of major gastrointestinal surgery * Diagnosed diabetes or use of lipid-lowering therapy * Known fat malabsorption disorders * Pregnant or lactating women * Post-menopausal women * Following a restrictive or specific diet (e.g. vegan, ketogenic diet) * Food allergies or intolerances relevant to study interventions (e.g. dairy, coconut) * Recent significant weight change (±2 kg in the past month) * High reliance on ready meals or takeaway foods (\>7 main meals per week) * Participation in another research study that may interfere with this study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood lipid profiles Gut microbiota diversity and composition Inflammation biomarkers Short chain fatty acids concentration in stools

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • New Lister Building, Glasgow Royal Infirmary, 10-16 Alexandra Parade, G31 2ER

    RECRUITING

    Glasgow, G31 2ER, United Kingdom

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