Could a daily supplement combo ease joint pain and fatigue in midlife women?
NCT ID NCT07740967
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study tests whether taking collagen peptides and omega-3 supplements daily for 8 weeks can improve health and wellbeing in healthy women aged 35-65. Researchers will measure joint pain, fatigue, sleep, body composition, strength, and inflammation before and after supplementation. Participants are randomly assigned to receive the supplements or a placebo (maltodextrin). The goal is to see if this combination can address common midlife concerns like joint discomfort and low energy.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Collagen peptides and omega-3 supplements
- What this could lead to
- If effective, this combination could offer a simple, non-drug way to ease joint pain, fatigue, and sleep issues in middle-aged women.
- What could go wrong
- The trial is small (34 participants) and short (8 weeks), so results may not apply broadly. Supplements may have modest effects or none compared to placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 34 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female * Age 35 - 65 years old * Healthy, free from known disease * Non-smoker * BMI of 18 - 30 kg/m2 of * Classified as either recreationally physically active (meet the WHO guidelines for physical activity of completing at least 150-300 min moderate-intensity activity or 75-150 min of vigorous-intensity activity a week, plus muscle-strengthening activities 2 or more days a week) OR classified as sedentary (do not meet minimum activity guidelines but do occasional and/or incidental physical activity (e.g., walking to work, household activities)) Exclusion Criteria: * Currently have a musculoskeletal injury or diagnosed condition (e.g., cardiovascular disease, osteoarthritis, diabetes, cancer, metabolic syndrome, uncontrolled hypertension, gastrointestinal disease, blood clotting disorder) * Regularly taking prescription medication initiated in the last 3 months or unstable * Have initiated hormone replacement therapy within the last 3 months and/or currently unstable * BMI not between 18-30 kg/m2 * Allergy to ingredients in supplements or standardized breakfasts * Pregnant or breastfeeding, or any other contraindications to consuming study supplements * Lost more than 10% of body mass in past 6 months or plan on trying to lose body mass during trial period * Currently consuming the supplements being investigated and unwilling to stop taking them * Any known cognitive or visual impairments limiting ability to perform cognitive tests * Unwilling to maintain current diet and physical activity levels or exercise and activity levels above recreationally active (e.g., athlete)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Loughborough University
RECRUITINGLoughborough, LE11 3TU, United Kingdom
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