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Bouillon boost: can broth cubes fight vitamin a deficiency?

NCT ID NCT06438562

Knowledge-focused Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested how well vitamin A is absorbed from fortified bouillon cubes compared to an oil-based supplement. Fifty-eight healthy women consumed different vitamin A formulations in broth, and researchers measured vitamin levels in their blood. The goal is to see if adding vitamin A to bouillon could help address deficiency in low-income countries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

58 people

The number who actually took part.

Started

Jul 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 49 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy, nonpregnant women * ≥18 and \<49 years of age * Able and willing to provide informed consent * Body mass index (BMI) between 18.5 to 30.0 kg/m2 * Willing and able to undergo study procedures, including: repeated blood sampling, a baseline hemoglobin and pregnancy test, adherence to a low-vitamin A diet at specified times throughout the study, consumption of provided meals (specifically, a breakfast of bouillon, peanut butter, and a bagel or bread), and, except for the Screening visit, foregoing alcohol for at least 2 days before each visit and fasting for ≥8 hours before each visit Exclusion Criteria: * Currently pregnant * Breastfeeding a child under 1 year of age * Allergic to soy or peanut butter * Current use of smoking tobacco products or any other form of nicotine * Active eating disorder diagnosis * Current diagnosis of acute or chronic illness, including hepatitis, Celiac's disease, Crohn's disease, and cystic fibrosis * Moderate or severe anemia according to World Health Organization guidelines (i.e., hemoglobin ≤10.9 g/dL) * Unable or unwilling to refrain from consuming alcohol when required * Unable or unwilling to discontinue consumption of foods that are high in vitamin A and of vitamin A supplements when required during the study * Taking prescription oral medication that includes a retinoid, e.g., isotretinoin/ Accutane * Taking proton pump inhibitors. * Unable/unwilling to avoid taking antacids during the fasting period prior to sample collection * Unable/unwilling to fast for periods of at least 10 hours at a time * Status relationship with a member of the study team. * Unable to fulfill study requirements per the judgment of the investigator

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Conditions

The condition(s) this trial relates to.

vitamin A deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteers Vitamin A

Contacts and locations

Locations

  • Tropical Diseases Research Centre - Field Office

    Rufunsa, Zambia

  • University of Wisconsin-Madison

    Madison, Wisconsin, 53706, United States

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