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Could a drug combo boost Chemo's power against breast cancer?

NCT ID NCT01251874

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 21 times

Summary

This early-phase trial tested the safety and best dose of combining veliparib with the chemotherapy drug carboplatin in 44 people with HER2-negative breast cancer that had spread. The goal was to see if veliparib could stop cancer cells from repairing damage caused by carboplatin, potentially making the chemo more effective. The study focused on side effects and tumor response, not a cure.

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Contacts and locations

Locations

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.