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New varicocele surgery technique shows promise for male fertility

NCT ID NCT07306572

Disease control Sponsor: Fayoum University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two surgical methods to repair varicoceles (enlarged veins in the scrotum) in 60 men with fertility issues or pain. One group had a loupe-assisted surgery with a nitroglycerin spray to help see blood vessels, while the other had standard microscopic surgery. The goal was to see which method better improved sperm movement and testicular blood flow three months after the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

May 2023

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with clinically evident varicocele who presented with primary or secondary infertility * intractable pain * aberrant semen values * and diminished testicular volume were included in the study. Exclusion Criteria: * Those with systemic conditions that impact arterial flow, such as diabetes, hypertension, liver disease, and hypercholesterolemia * Younger than 18 or older than 50. * Patients with subclinical varicocele * patients had previously had a varicocelectomy or inguinoscrotal surgery on the same side were not included.

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Conditions

The condition(s) this trial relates to.

varicocele

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Microscopic varicocelectomy Nitroglycerine instillation in loop-assisted varicocelectomy

Contacts and locations

Locations

  • Mohamed Mahmoud Dogha

    Al Fayyum, 63514, Egypt

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