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Which route to the vein works best for varicocele repair?

NCT ID NCT07764900

Disease control Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial is testing two different ways to perform varicocele embolization, a procedure that blocks off enlarged veins in the scrotum to relieve pain and improve fertility. Thirty men with varicocele will receive the procedure either through a vein in the neck (transjugular) or through a vein in the groin (transfemoral), depending on their anatomy. The study will compare how well each approach reduces pain and improves symptoms at one and three months after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Percutaneous varicocele embolization using N-butyl cyanoacrylate (NBCA) glue, performed via either a transjugular or transfemoral approach.
What this could lead to
If successful, this could help doctors choose the best vein-access route for varicocele embolization, potentially improving pain relief and fertility outcomes with fewer complications.
What could go wrong
This is a small, early-stage study with only 30 patients, so results may not apply to everyone. The procedure carries risks like bleeding, infection, or glue migration, and the best approach may depend on individual anatomy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 60 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Male patients aged 16-60 years. 2. Clinically palpable varicocele (Grade II or III) or subclinical varicocele associated with abnormal semen parameters. 3\. Recurrent varicocele following previous surgical treatment. 4. Presence of scrotal pain, testicular atrophy, or infertility attributed to varicocele. 5\. Willingness to participate in the study and provide written informed consent. Exclusion Criteria: \- 1. Secondary varicocele due to a retroperitoneal mass or renal vein obstruction. 2\. Known allergy to iodinated contrast media. 3. Coagulation disorders or contraindications to endovascular procedures.

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Conditions

The condition(s) this trial relates to.

varicocele

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Varicocele

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag University - Faculty of Medicine

    RECRUITING

    Sohag, Sohag Governorate, 82524, Egypt

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