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Massage therapy could boost sperm quality in men with varicocele

NCT ID NCT07665905

Disease control Sponsor: Ankara Yildirim Beyazıt University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a type of abdominal massage called visceral osteopathic manual therapy can improve sperm quality and blood flow in men with varicocele, a condition where veins in the scrotum become enlarged and can cause infertility. Thirty-two men aged 18-45 will either receive the massage twice a week for eight weeks or just get lifestyle advice. Researchers will compare semen samples and ultrasound measures before and after treatment to see if the massage helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
visceral osteopathic manual therapy (massage techniques)
What this could lead to
If it works, this could offer a non-surgical, low-cost option to improve fertility in men with varicocele.
What could go wrong
This is a small, early-stage trial with only 32 participants, so results may not apply to everyone. The treatment is manual therapy, which depends on the therapist's skill and may not produce consistent outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male individuals aged 18-45 years. 2. Diagnosis of varicocele confirmed by clinical examination and Doppler Ultrasound. 3. Not being considered a candidate for surgery by a urology specialist. 4. Following a follow-up protocol based on spermiogram results. 5. Having at least one varicocele-related abnormality in spermiogram parameters according to WHO 2021 standards. 6. Providing voluntary consent to participate in the study. Exclusion Criteria: 1. History of prior inguinal or scrotal surgery. 2. Presence of active urogenital infection or malignancy. 3. History of spinal or abdominal surgery that would contraindicate complementary medicine interventions. 4. Having systemic inflammatory, rheumatologic, or endocrinologic diseases. 5. Receiving additional medical or surgical intervention during the study period beyond routine medical treatment. 6. Sperm quality changes due to hypogonadotropic causes. 7. Use of prescribed purified flavonoid fraction venotonics for venous congestion and endothelial dysfunction. 8. Use of antioxidant supplements (e.g., L-carnitine, L-acetylcarnitine, Ubiquinol, etc.) intended to improve sperm quality. 9. Refusal to participate in the study.

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Conditions

The condition(s) this trial relates to.

infertility disorder varicocele

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infertility Varicocele

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Etlik Lokman Hekim Hospital, Clinic of Urology

    Ankara, Keçiören, 06300, Turkey (Türkiye)

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