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New CT angle may predict kidney stone surgery complications

NCT ID NCT07561684

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Recruiting now
This trial is taking on new participants right now.
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Registered, but not yet taking participants.
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Not open to general applications. Only people the study team invites can take part.
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Running, but no longer taking on new participants.
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The trial has finished. Results may not be published yet.
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Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a special CT measurement, called the URSL Predictive Angle, can help doctors know ahead of time if a kidney stone surgery might need to switch to a different method during the procedure. Researchers will review records from 2,200 patients who had this surgery between 2018 and 2025. The goal is to reduce risks like longer surgery time and extra stress on patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All participating centers are required to maintain established expertise in ureteroscopic surgical techniques, robust clinical data management infrastructure, and comprehensive archival systems for preoperative computed tomography imaging. Each center shall formally assent to and comply with the unified study protocol, thereby ensuring data completeness, source traceability, and adherence to international ethical standards. Eligible patient records will be retrieved for the period spanning January 1, 2018, to December 31, 2025 (inclusive, encompassing an eight-year interval). All patients who underwent URSL for ureteral calculi and satisfied the stipulated eligibility criteria during this timeframe will be considered for inclusion.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age \> 18 years at the time of surgery, without restriction based on sex, ethnicity, or occupation. 2. Preoperative imaging confirmation of unilateral, solitary, or unilateral multiple ureteral calculi. In cases of ipsilateral multiple stones, the calculus deemed primarily responsible for obstruction or designated as the principal surgical target shall serve as the index stone. 3. Planned and attempted transurethral ureteroscopic lithotripsy as the initial treatment modality. 4. Availability of preoperative thin-slice (section thickness ≤ 1.25 mm) computed tomography urography or non-contrast CT of the urinary tract in native Digital Imaging and Communications in Medicine (DICOM) format, of sufficient diagnostic quality to permit multiplanar reconstruction and precise morphometric analysis. Image data must be complete and free from substantial motion or beam-hardening artifact that would preclude accurate delineation of ureteral anatomy. Exclusion Criteria: * 1.Absence of preoperative CT imaging performed at the participating institution; missing, corrupted, or irretrievable DICOM data; or suboptimal image quality that precludes reliable ureteral segmentation and measurement. 2.Incomplete inpatient medical records lacking essential demographic or baseline clinical data; operative notes containing insufficient procedural detail to definitively ascertain whether intraoperative conversion occurred or to adjudicate the specific etiology thereof. 3.Prior ipsilateral percutaneous nephrostomy tube placement or ureteral stent indwelling for any indication before the index URSL procedure. 4.Calculi situated at anatomically distinct locations, specifically the ureteropelvic junction or the ureteral orifice. 5.Antecedent ipsilateral ureteral surgery (e.g., ureteral reimplantation, prior ureteroscopic lithotripsy) or history of urinary diversion (e.g., ileal conduit). Such patients are excluded because surgical alteration of native ureteral anatomy would confound the morphometric assumptions underlying URSL angle determination.

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Conditions

The condition(s) this trial relates to.

Ureteral Calculi ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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