Machine learning may crack the code of OCD therapy
NCT ID NCT06173752
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is observing 400 adults with OCD who are receiving exposure therapy. Researchers will use machine learning to analyze self-reports, behavior, and physiological data from therapy sessions. The goal is to identify which mechanisms lead to better outcomes, so therapy can be improved for those who don't fully recover.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exposure therapy
- What this could lead to
- If successful, this could help personalize exposure therapy for OCD, making it more effective for more people.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results depend on complex data analysis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Between the ages of 18-65 years old * Seeking exposure treatment at McLean Hospital OCD Institute or San Diego State University * Have a diagnosis of OCD * Able to complete study measures and treatment procedures in English Exclusion Criteria: * Acute symptoms of psychosis * Active suicidality (plan, means, intent and/or suicide attempt in past 3 months) * Presence of co-occurring symptoms that warrant higher level of care (e.g., inpatient treatment) * Presence of any medical, psychiatric, or developmental condition that would prevent patients from completing assessments or exposure exercises (e.g., non-verbal autism spectrum disorder)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Center for Understanding and Treating Anxiety
RECRUITINGSan Diego, California, 92120, United States
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McLean OCDI
RECRUITINGBelmont, Massachusetts, 02478, United States
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