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New bladder cancer drug shows promise in early trial

NCT ID NCT05375903

First seen Jan 19, 2026 · Last updated May 22, 2026 · Updated 15 times

Summary

This early-phase study tested a new drug called UGN-301 (zalifrelimab) in 51 people with recurrent non-muscle invasive bladder cancer. The goal was to check the drug's safety and find the best dose when given directly into the bladder, alone or with other treatments. Results will help guide future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Arkansas Urology

    Little Rock, Arkansas, 72211, United States

  • Clinical Research Solutions

    Middleburg Heights, Ohio, 44130, United States

  • Florida Urology Partners, LLC

    Tampa, Florida, 33615, United States

  • Hospital Clinic de Barcelona Instituto Clinic de Nefrologia y Urologia (ICNU)

    Barcelona, 08036, Spain

  • I.R.C.C.S. Ospedale San Raffaele

    Milan, Italy

  • Istituto Oncologico Veneto

    Padova, Italy

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Manhattan Medical Research

    New York, New York, 10016, United States

  • NEXT Oncology IOB- Hospital Quironsalud Barcelona

    Barcelona, 08023, Spain

  • NEXT Oncology- Hospital Quironsalud Mardrid

    Madrid, 28223, Spain

  • National Tumor Institute Fondazione G. Pascale

    Naples, Italy

  • Penn State Milton S Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • UCLA - University of California

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.