UROTHELIAL CARCINOMA BLADDER

This study is testing a combination of two drugs, enfortumab vedotin and pembrolizumab, for patients with high-grade cancer in their kidney or ureter who are not candidates for or refuse the standard surgery to remove the organ. The goal is to see if this drug treatment can contr…

This study is testing a new type of cancer drug that delivers radiation directly to tumors by targeting a protein called Nectin-4. It aims to find a safe and effective dose for patients with advanced solid cancers who have already tried other treatments. The trial will first dete…

This study is testing a decision-making tool to help surgeons decide which women with bladder cancer can safely have a less invasive surgery. The goal is to avoid removing healthy reproductive organs during bladder removal, which may improve long-term quality of life, sexual heal…

This trial tests a new type of immune cell therapy called 4SCAR-T for people with advanced bladder cancer that has spread and who have run out of standard treatment options. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cancer cell…

This early-stage trial is testing a new drug called belzupacap sarotalocan (AU-011) for bladder cancer that hasn't spread into the muscle wall. Researchers will inject the drug directly into tumors during a standard bladder procedure to see if it's safe and practical to use. The …

This study aims to develop and test a new diagnostic tool that uses artificial intelligence (AI) to analyze small pieces of a patient's tumor. The goal is to predict whether a patient will respond to certain immunotherapy cancer drugs before they start treatment. Researchers will…

This study is testing a new urine test called Bladder EpiCheck to see how well it can detect bladder cancer in people aged 45 and older who have blood in their urine. Researchers will compare the test's accuracy to the current standard method, which involves a camera exam of the …