UROTHELIAL CARCINOMA BLADDER

This study tests a drug called UGN-102 for people with a low-grade, intermediate-risk type of bladder cancer that hasn't spread into the muscle. The goal is to see if this drug can destroy the cancer without needing surgery. About 240 participants received the drug, and researche…

This study tests a new approach for people with muscle-invasive bladder cancer who cannot receive standard chemotherapy. It combines an immunotherapy drug (sasanlimab) with targeted radiation to boost the immune system's ability to fight the tumor before surgical removal of the b…

This study tests a new drug called RNDO-564, alone or with another drug (pembrolizumab), in people with advanced solid tumors (like lung, bladder, or breast cancer) that no longer respond to standard treatments. The main goals are to check safety, find the best dose, and see if t…

This study was testing a drug called NDV-01 (a combination of two chemotherapy medicines) for people with a type of bladder cancer that did not respond to the usual BCG treatment. The goal was to see if the drug could make the cancer disappear and help patients avoid having their…

This study tests a new drug called UGN-103, which is placed directly into the bladder, to treat a type of low-grade bladder cancer that hasn't spread into the muscle. About 99 people with this cancer at intermediate risk of coming back will receive the treatment. The main goal is…

This study was designed to test a new treatment called NDV-01 for people with a certain type of bladder cancer that hasn't spread into the muscle. The plan was to compare the drug against simply watching and waiting after surgery. However, the trial was withdrawn before any parti…

This early-stage study tests an experimental drug called BL-M17D1 in 120 adults with advanced solid tumors that have a specific protein (HER2) or a HER2 gene change. The main goals are to check the drug's safety, find the right dose, and see if it shrinks tumors. Participants mus…

This study tests a combination of two chemotherapy drugs, gemcitabine and docetaxel, given directly into the bladder for people with early-stage bladder cancer who have not received standard BCG therapy. The goal is to see if this treatment can clear the cancer and keep it from c…

This study looks at a urine test called Bladder CARE Assay to see if it can accurately detect bladder cancer in people whose standard tests (cystoscopy or cytology) were not clear. About 80 adults with suspicious but inconclusive results will provide a urine sample before their n…

This study collects fresh tumor samples from 416 adults with various cancers (bladder, kidney, colorectal, head and neck, liver, lung, skin, endometrial) to develop and train a live tumor diagnostic platform. The goal is to see how accurately the platform can predict whether a pa…