UROTHELIAL CARCINOMA BLADDER

This early-stage study is testing a new drug called RNDO-564, both by itself and combined with an existing immunotherapy (pembrolizumab), in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find safe dose levels and see …

This study is testing a new combination treatment for early-stage bladder cancer in patients who haven't received the standard BCG therapy. Participants receive the drugs directly into the bladder through a catheter, starting with weekly treatments for six weeks, then monthly if …

This study planned to test whether a new drug called NDV-01 could help prevent cancer from coming back in people with intermediate-risk, non-muscle invasive bladder cancer. Participants would have had their tumors removed and then been randomly assigned to either receive the drug…

This is the first human study testing the safety and early effects of an experimental drug called BL-M17D1 in people with advanced cancers that have a specific marker called HER2. The trial will enroll 120 adults with various hard-to-treat cancers, including breast, lung, and sto…

This study is testing a new two-part treatment for muscle-invasive bladder cancer in patients who cannot receive standard chemotherapy. Before having their bladder surgically removed, participants receive a drug called sasanlimab (an immunotherapy) and a short, precise course of …

This study is testing a new liquid treatment called UGN-103 for people with a specific type of early-stage bladder cancer that has a moderate risk of returning. The treatment is placed directly into the bladder once a week for six weeks. Researchers want to see if it can complete…

This study planned to test a new bladder cancer treatment called NDV-01 for patients whose cancer returned after standard therapies. The treatment would have been delivered directly into the bladder to try to control the cancer and potentially avoid major surgery. However, the tr…

This study is testing a new urine test called Bladder CARE™ to see if it can accurately detect bladder cancer in patients whose standard test results are unclear or uncertain. Researchers will collect a urine sample from 80 participants before their scheduled bladder exam and the…