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New drug aims to shrink hard-to-treat HER2 cancers in early trial

NCT ID NCT06714617

First seen Nov 05, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This early-phase study tests a new drug called BL-M17D1 in 120 adults with advanced solid tumors that have HER2 changes (either too much HER2 protein or a HER2 gene mutation). The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. Participants must have already tried at least one standard treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Hematology Oncology Associates of the Treasure Cost

    Port Saint Lucie, Florida, 34952, United States

  • NEXT Oncology

    Fairfax, Virginia, 22031, United States

  • SCRI-Denver HealthOne

    Denver, Colorado, 37203, United States

  • SCRI-Florida Cancer Center Specialists Lake Mary

    Lake Mary, Florida, 32746, United States

  • SCRI-Florida Cancer Center Specialists Sarasota

    Sarasota, Florida, 34236, United States

  • SCRI-Oncology Partners

    Nashville, Tennessee, 37203, United States

  • SCRI-Sidney Kimmel Cancer Center

    Philadelphia, Pennsylvania, 19107, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.