New bladder cancer drug shows promise in early trial

NCT ID NCT05375903

First seen Jan 19, 2026 · Last updated May 14, 2026 · Updated 14 times

Summary

This early-stage study tested a new drug called UGN-301 (zalifrelimab) in 51 people with recurrent non-muscle invasive bladder cancer. The drug was given directly into the bladder to see if it is safe and to find the best dose. The goal is to control the cancer and prevent it from coming back.

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Contacts and locations

Locations

  • Arkansas Urology

    Little Rock, Arkansas, 72211, United States

  • Clinical Research Solutions

    Middleburg Heights, Ohio, 44130, United States

  • Florida Urology Partners, LLC

    Tampa, Florida, 33615, United States

  • Hospital Clinic de Barcelona Instituto Clinic de Nefrologia y Urologia (ICNU)

    Barcelona, 08036, Spain

  • I.R.C.C.S. Ospedale San Raffaele

    Milan, Italy

  • Istituto Oncologico Veneto

    Padova, Italy

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Manhattan Medical Research

    New York, New York, 10016, United States

  • NEXT Oncology IOB- Hospital Quironsalud Barcelona

    Barcelona, 08023, Spain

  • NEXT Oncology- Hospital Quironsalud Mardrid

    Madrid, 28223, Spain

  • National Tumor Institute Fondazione G. Pascale

    Naples, Italy

  • Penn State Milton S Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • UCLA - University of California

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.