Could less dialysis be better for seniors? new study aims to find out
NCT ID NCT06141798
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares starting dialysis twice a week versus the standard three times a week in elderly patients (60+) with end-stage kidney disease who still produce some urine. The goal is to see if fewer sessions reduce hospitalizations, falls, and other complications while maintaining quality of life. Over 400 participants will be followed for up to two years.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Hemodialysis (number of sessions per week)
- What this could lead to
- If successful, this could show that starting dialysis twice a week is safer and reduces hospital stays for elderly patients, potentially changing standard care.
- What could go wrong
- This is a pragmatic trial, but results may not apply to all patients. Twice-weekly dialysis might not control toxins well enough, and the study is limited to those with residual kidney function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 428 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2021
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥60 years * Clinical diagnosis of end stage kidney disease * Starting maintenance hemodialysis within one month * 24-hour urine output ≥ 500 ml at randomization * Sufficient understanding of the study procedures and requirements. Exclusion Criteria: * Left ventricular ejection fraction \< 40%) * Liver cirrhosis * Current treatment for an active malignancy or active infection * Onability or refusal to provide written informed consent * enrollment in another clinical trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hallym University Medical Center- Chuncheon
COMPLETEDChuncheon, South Korea
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Kangbuk Samsung Medical Center
COMPLETEDSeoul, South Korea
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Koera University Guro Hospital
COMPLETEDSeoul, South Korea
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Soonchunhyang University Hospital Bucheon
RECRUITINGBucheon-si, South Korea
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Soonchunhyang University Seoul Hospital
ACTIVE_NOT_RECRUITINGSeoul, 04401, South Korea
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The Catholic University of Korea, Yeouido St. Mary's Hospital
COMPLETEDSeoul, South Korea
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Yonsei University, Wonju Severance Christian Hospital
COMPLETEDWŏnju, South Korea
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