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New drug shows promise for rare movement disorder

NCT ID NCT02960893

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 32 times

Summary

This study tested a daily pill called troriluzole in 141 adults with spinocerebellar ataxia, a rare genetic disease that affects balance and coordination. Participants took either the drug or a placebo for 8 weeks. The main goal was to see if troriluzole could improve symptoms like walking and hand movements, measured by a standard ataxia rating scale.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CNS Trial

    Long Beach, California, 90806, United States

  • Columbia University

    New York, New York, 10032, United States

  • Emory University

    Atlanta, Georgia, 30329, United States

  • Harvard University (Beth Israel Deaconess Medical Center)

    Boston, Massachusetts, 02215, United States

  • Harvard University (Massachusetts General Hospital)

    Boston, Massachusetts, 02114, United States

  • Houston Methodist Research Center

    Houston, Texas, 77030, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • St. Joseph's Hospital and Medical Center

    Phoenix, Arizona, 85013, United States

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

  • University of California, San Francisco

    San Francisco, California, 94158, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Colorado Denver

    Denver, Colorado, 80045, United States

  • University of Florida

    Gainesville, Florida, 32611, United States

  • University of Michigan

    Ann Arbor, Michigan, 48105, United States

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • University of South Florida

    Tampa, Florida, 33612, United States

  • University of Texas Southwestern

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.