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Could a bad mood or infection trigger a major stroke? scientists investigate

NCT ID NCT06265155

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to identify short-term triggers of acute ischemic stroke caused by large vessel occlusion, a severe type of stroke. Researchers will ask 302 patients about their exposure to potential triggers—such as infection, mood changes, smoking, alcohol, diarrhea, and extreme temperatures—in the year before their stroke and just before it happened. By comparing these time periods, they hope to pinpoint which factors may increase stroke risk in the hours or days prior.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify specific triggers that raise the short-term risk of severe stroke, helping people avoid them and potentially reducing stroke incidence.
What could go wrong
This is an observational study, not a treatment trial. It can only suggest associations, not prove cause and effect. Recall bias may affect results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

302 people

The number who actually took part.

Started

Feb 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with ischemic stroke due to large vessel occlusion。

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. age ≥ 18 years 2. imaging diagnosis of large vessel occlusion 3. CT excluded intracranial hemorrhage 4. signed informed consent form by the patient himself or his legal representative Exclusion Criteria: 1. severe bleeding or known significant bleeding tendency 2. severe organ dysfunction 3. life expectancy of less than 90 days 4. presence of other conditions that the investigator considers inappropriate for enrollment

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Suzhou Hospital Anhui Medical University

    Suzhou, Anhui, 234000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.