Could a bad mood or infection trigger a major stroke? scientists investigate
NCT ID NCT06265155
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to identify short-term triggers of acute ischemic stroke caused by large vessel occlusion, a severe type of stroke. Researchers will ask 302 patients about their exposure to potential triggers—such as infection, mood changes, smoking, alcohol, diarrhea, and extreme temperatures—in the year before their stroke and just before it happened. By comparing these time periods, they hope to pinpoint which factors may increase stroke risk in the hours or days prior.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify specific triggers that raise the short-term risk of severe stroke, helping people avoid them and potentially reducing stroke incidence.
- What could go wrong
- This is an observational study, not a treatment trial. It can only suggest associations, not prove cause and effect. Recall bias may affect results.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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302 people
The number who actually took part.
- Started
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Feb 2024
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with ischemic stroke due to large vessel occlusion。
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. age ≥ 18 years 2. imaging diagnosis of large vessel occlusion 3. CT excluded intracranial hemorrhage 4. signed informed consent form by the patient himself or his legal representative Exclusion Criteria: 1. severe bleeding or known significant bleeding tendency 2. severe organ dysfunction 3. life expectancy of less than 90 days 4. presence of other conditions that the investigator considers inappropriate for enrollment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Suzhou Hospital Anhui Medical University
Suzhou, Anhui, 234000, China
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Other studies related to the condition(s) this trial covers.
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