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Blood test may replace painful biopsies for lung transplant patients

NCT ID NCT05837663

First seen Nov 17, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study aims to see if a blood test (dd-cfDNA) can accurately detect lung transplant rejection compared to standard biopsy methods. Researchers will enroll 600 adult lung transplant recipients to compare blood test results with tissue analysis and antibody tests. The goal is to make rejection monitoring easier and less invasive for patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alberta Transplant Applied Genomics Centre, University of Alberta

    RECRUITING

    Edmonton, Alberta, T^g 2E1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BAYLOR SCOTT & WHITE RESEARCH INSTITUTE , 3409 Worth Street

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Charles University/Hospital Motol

    RECRUITING

    Prague, Czechia

    Contact Email: •••••@•••••

    Contact

  • Department of Medicine, University of Alberta

    RECRUITING

    Edmonton, Alberta, T6G 2G3, Canada

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Thoracic Surgery, Medical University of Vienna

    NOT_YET_RECRUITING

    Vienna, Austria

    Contact Email: •••••@•••••

    Contact

    Contact

  • Division of Pulmonary, Allergy & Critical Care Medicine Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Email: •••••@•••••

  • Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of Medicine

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact

    Contact

    Contact Email: •••••@•••••

    Contact

  • Houston Methodist Lung Transplant Center, 6550 Fannin St., SM1001

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • Indiana University Methodist Hospital 1812 N. Capitol Ave Suite W131L

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Email: •••••@•••••

    Contact

  • Johns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans Street

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Email: •••••@•••••

    Contact

  • Motol University Hospital, V Uvalu 84

    RECRUITING

    Prague, 15006, Czechia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT

    RECRUITING

    Phoenix, Arizona, 85013, United States

    Contact Email: •••••@•••••

    Contact

  • The Alfred Hospital, Monash University

    RECRUITING

    Melbourne, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • The Ohio State University Wexner Medical Center, 410 W 10th Ave

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

    Contact

  • USF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Email: •••••@•••••

    Contact

  • UT Health San Antonio 7703 Floyd Curl Drive, MSC: 7858

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Email: •••••@•••••

  • UT Southwestern Medical Center, 5939 Harry Hines Blvd.

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••

    Contact

  • University Health Network, Toronto General Hospital

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

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