New study tests safer wrist access for heart patients with blocked arteries

NCT ID NCT07380399

Knowledge-focused Sponsor: National and Kapodistrian University of Athens Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for adults with a blocked radial artery who need a heart procedure like angiography or angioplasty. Doctors will use the ulnar artery in the same wrist instead. The goal is to see if this approach is safe and how it affects hand strength, feeling, and daily use. Researchers will follow 127 participants to track complications and hand function over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to: If successful, this study could provide evidence that using the ulnar artery is a safe alternative for heart procedures when the radial artery is blocked, improving patient care.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test a new therapy. The results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 127 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Jan 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants are recruited from cardiac catheterization laboratories and cardiology services of two tertiary-care public hospitals in Greece, including high-volume referral centers performing invasive coronary procedures. The study population represents adults undergoing routine elective coronary angiography or angioplasty in these hospital settings, where vascular access decisions are made as part of standard clinical practice.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria Participants must meet all of the following criteria to be eligible: * Adults aged 18 years or older * Documented radial artery occlusion in the upper limb intended for vascular access, confirmed by ultrasound or angiography * Scheduled to undergo elective coronary angiography and/or angioplasty * Transulnar arterial access on the same side as the occluded radial artery is selected by the treating physician * Contralateral radial artery access is not feasible or is clinically undesirable, including for reasons such as: * documented occlusion or severe disease of the contralateral radial artery * unfavorable anatomy or prior failed access * strategic preservation of the contralateral radial artery for future surgical or dialysis needs * Adequate ulnar artery flow and anatomy for access, as assessed by pre-procedural ultrasound * Able and willing to provide written informed consent Exclusion Criteria Participants meeting any of the following criteria will be excluded: * Inadequate or absent ulnar artery flow at the intended access site on ultrasound * Known ulnar nerve injury or neuropathy affecting the access-side upper limb * Severe pre-existing motor or sensory dysfunction of the access-side hand that would interfere with functional assessment * Emergency coronary procedures that preclude baseline vascular or functional assessment * Participation in another interventional clinical study involving vascular access or intervention in the same upper limb * Local conditions at the intended access site, such as active infection, burn, or extensive scarring * Pregnancy or breastfeeding * Life expectancy less than 6 months

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Conditions

The condition(s) this trial relates to.

arterial occlusion Arterial Occlusive Diseases coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease (CAD) Radial artery occlusion Vascular access

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

2 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

New study tests safer wrist access for heart patients with blocked arteries

What the study statuses mean