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A simple ultrasound might replace invasive pressure monitoring

NCT ID NCT07773506

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive ultrasound of the internal jugular vein in the neck can estimate central venous pressure (CVP), a key measure of fluid status in critically ill patients. Traditionally, doctors estimate this by looking at the neck veins, but that is often inaccurate, especially in obese or very ill patients. The study will compare ultrasound measurements of vein diameter and collapsibility with direct pressure readings in 100 adults who need a central line. If the ultrasound matches well, it could offer a safer, easier way to monitor patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vascular ultrasound (Doppler) examination of the internal jugular vein
What this could lead to
If ultrasound reliably estimates central venous pressure, it could offer a non-invasive way to assess fluid status in critically ill patients, reducing the need for invasive monitoring.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Ultrasound measurements may not correlate perfectly with direct pressure readings, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 18 years or older admitted to the Intensive Care Unit (ICU), Emergency Department, or Operating Theatres at Assiut University Hospitals who require ultrasound-guided right internal jugular vein (IJV) cannulation and hemodynamic assessment for clinical indications.

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older. * Patients admitted to the Intensive Care Unit (ICU), Emergency Department, or Operating Theatres who require internal jugular vein (IJV) cannulation for clinical indications. * Patients in whom ultrasound-guided right internal jugular vein cannulation is planned. * Patients who are hemodynamically stable enough to undergo ultrasound examination before cannulation. * Patients able to undergo vascular ultrasound examination in the supine position (0-30° head elevation according to the study protocol). * Patients in whom complete ultrasound assessment of the internal jugular vein can be performed (including maximum diameter, minimum diameter, cross-sectional area, and collapsibility/distensibility index). * Patients with a clinically indicated assessment of central venous pressure (CVP) or jugular venous pressure (JVP) allowing comparison with ultrasound measurements. * Patients providing written informed consent, or consent obtained from a legally authorized representative when applicable. Exclusion Criteria: * Patients younger than 18 years of age. * Previous surgery, radiotherapy, or significant trauma involving the neck. * Known thrombosis, stenosis, or congenital anomalies of the internal jugular vein. * Local infection, cellulitis, burn, or hematoma at the intended cannulation site. * Large neck masses, thyroid enlargement, or cervical pathology causing distortion of neck anatomy. * Severe coagulopathy or uncontrolled bleeding disorders contraindicating internal jugular vein cannulation. * Patients with cervical spine instability or those in whom proper positioning for ultrasound examination is not possible. * Inadequate ultrasound visualization of the internal jugular vein. * Severe tricuspid valve disease or conditions causing marked alterations in central venous hemodynamics that interfere with accurate interpretation of IJV measurements. * Refusal of the patient or legally authorized representative to provide informed consent.

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How to take part

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