A simple ultrasound might replace invasive pressure monitoring
NCT ID NCT07773506
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive ultrasound of the internal jugular vein in the neck can estimate central venous pressure (CVP), a key measure of fluid status in critically ill patients. Traditionally, doctors estimate this by looking at the neck veins, but that is often inaccurate, especially in obese or very ill patients. The study will compare ultrasound measurements of vein diameter and collapsibility with direct pressure readings in 100 adults who need a central line. If the ultrasound matches well, it could offer a safer, easier way to monitor patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vascular ultrasound (Doppler) examination of the internal jugular vein
- What this could lead to
- If ultrasound reliably estimates central venous pressure, it could offer a non-invasive way to assess fluid status in critically ill patients, reducing the need for invasive monitoring.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. Ultrasound measurements may not correlate perfectly with direct pressure readings, and results may not apply to all patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients aged 18 years or older admitted to the Intensive Care Unit (ICU), Emergency Department, or Operating Theatres at Assiut University Hospitals who require ultrasound-guided right internal jugular vein (IJV) cannulation and hemodynamic assessment for clinical indications.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 18 years or older. * Patients admitted to the Intensive Care Unit (ICU), Emergency Department, or Operating Theatres who require internal jugular vein (IJV) cannulation for clinical indications. * Patients in whom ultrasound-guided right internal jugular vein cannulation is planned. * Patients who are hemodynamically stable enough to undergo ultrasound examination before cannulation. * Patients able to undergo vascular ultrasound examination in the supine position (0-30° head elevation according to the study protocol). * Patients in whom complete ultrasound assessment of the internal jugular vein can be performed (including maximum diameter, minimum diameter, cross-sectional area, and collapsibility/distensibility index). * Patients with a clinically indicated assessment of central venous pressure (CVP) or jugular venous pressure (JVP) allowing comparison with ultrasound measurements. * Patients providing written informed consent, or consent obtained from a legally authorized representative when applicable. Exclusion Criteria: * Patients younger than 18 years of age. * Previous surgery, radiotherapy, or significant trauma involving the neck. * Known thrombosis, stenosis, or congenital anomalies of the internal jugular vein. * Local infection, cellulitis, burn, or hematoma at the intended cannulation site. * Large neck masses, thyroid enlargement, or cervical pathology causing distortion of neck anatomy. * Severe coagulopathy or uncontrolled bleeding disorders contraindicating internal jugular vein cannulation. * Patients with cervical spine instability or those in whom proper positioning for ultrasound examination is not possible. * Inadequate ultrasound visualization of the internal jugular vein. * Severe tricuspid valve disease or conditions causing marked alterations in central venous hemodynamics that interfere with accurate interpretation of IJV measurements. * Refusal of the patient or legally authorized representative to provide informed consent.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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