Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a common drug make ACL surgery less painful?

NCT ID NCT07753161

Symptom relief Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial tests whether giving tranexamic acid during ACL reconstruction surgery reduces blood loss and pain afterward. The drug is given as two intravenous infusions around the time of surgery, compared to a placebo. The study includes 100 adults having primary ACL reconstruction with hamstring tendon harvesting. The main goal is to measure hemoglobin loss from before surgery to two days after, with pain and recovery also tracked.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tranexamic acid given as two intravenous infusions during ACL reconstruction surgery
What this could lead to
If effective, this could lead to a simple, safe addition to ACL surgery that reduces bleeding, pain, and recovery time.
What could go wrong
This is a small, early-stage trial. The benefit may be modest, and tranexamic acid carries a small risk of blood clots, though it is widely used in other surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Feb 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female patient aged over 18 years4 * Patient with a surgical indication for primary reconstruction of an isolated ACL, +/- requiring an anterolateral reconstruction procedure or meniscectomy/meniscal repair * Planned outpatient surgical procedure * Patient affiliated with or a beneficiary of a social security scheme * Patient informed about the study and having signed the informed consent form Exclusion Criteria: * Patient with a history of ACL surgery * Patient with a history of knee surgery other than meniscectomy * Patient with multi-ligament knee injuries (PCL, MCL, or LCL) * Patient with a contraindication to the use of tranexamic acid: Hypersensitivity to the active substance or any of the excipients, acute venous or arterial thrombosis, fibrinolytic states resulting from consumptive coagulopathy (except in states associated with predominant activation of the fibrinolytic system with acute severe hemorrhage), severe renal impairment (risk of accumulation), history of convulsions, intrathecal and intraventricular injections, intracerebral applications (risk of cerebral edema and convulsions) * Patient with a hemostatic disorder, undergoing treatment with VKAs or anticoagulants, or receiving hormone replacement therapy * Patient with hepatic impairment * Patient with renal impairment * Patient unable or not in a position to agree to the entire procedure and follow-up required by the study * Patient participating in another clinical study * Protected patient: adult under guardianship, curatorship, or other legal protection; deprived of liberty by judicial or administrative decision * Pregnant or breastfeeding woman * Patient hospitalized without consent

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hemoglobin are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemoglobin Ligamentoplasty

Contacts and locations

Locations

  • Hôpital Privé La Louvière

    Lille, 59000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.