Can a common drug make ACL surgery less painful?
NCT ID NCT07753161
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests whether giving tranexamic acid during ACL reconstruction surgery reduces blood loss and pain afterward. The drug is given as two intravenous infusions around the time of surgery, compared to a placebo. The study includes 100 adults having primary ACL reconstruction with hamstring tendon harvesting. The main goal is to measure hemoglobin loss from before surgery to two days after, with pain and recovery also tracked.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tranexamic acid given as two intravenous infusions during ACL reconstruction surgery
- What this could lead to
- If effective, this could lead to a simple, safe addition to ACL surgery that reduces bleeding, pain, and recovery time.
- What could go wrong
- This is a small, early-stage trial. The benefit may be modest, and tranexamic acid carries a small risk of blood clots, though it is widely used in other surgeries.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Privé La Louvière
Lille, 59000, France
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